I don't know what my blood markers are. My inflammation comes from a reaction to fluorescent light, through my eyes, that is ubiquitous today (overhead lighting at work, television, computer monitors, etc). LED lights have the same effect. The only lighting that does not is any form of incandescent. It has given me a degree of glaucoma. I suspect that my brain's sensitivity to this light is due to a degree of brain damage that I likely suffered in adolescence either from hitting my head repeatedly during sports (football, wrestling) or from washing my hands in solvents such as Toulene when I worked construction. It could also be from a brief period of drug use in my distant past. I also have an internet addiction issue that was exacerbated by not having a good career (I'd stay on the computer hour after hour, making my symptoms worse, attempting to figure out something to do with my life). This went on for years, but I'm now graduated from an MS program and have a good career to look forward to as long as my health holds. However, the internet habit remains and I average a bedtime of about 3 am, which wreaks havoc on my system. As I got better at handling my symptoms, I would push my body further, making anything I did for my health a wash. I am on the brink on breaking this habit I hope, as my life is about to change drastically due to changes in my daily schedule due to work.
I don't specifically target glutathione as I've found doing such difficult to do. NAC gives me heart symptoms. Whey doesn't do much for me, at least not on the level on which I would need it to. I actually feel a bit of an uptick in inflammation when I take whey, however brief. This is likely due to immune system stimulation. I've learned to avoid immune stimulating supplements, and have done much better since figuring out that I need to do so (no curcumin, etc). I'd be amenable to trying something like acetyl-glutathione, but I'd be wary of negatively affecting my baseline glutathione production.
After fourteen years of this inflammation, and dealing with it somewhat successfully after the first five years, I started having muscle symptoms this past year. Muscle twitching that would last for weeks in my thumb, with resultant muscle weakness that lasted for a couple of more weeks, and pain in muscles in my foot and arm. My memory also became worse. I started reading MS forums (which also tipped me to avoiding immune stimulating substances) and stumbled onto a recommendation for N-acetyl Glucosamine. I tried it and in fourteen years it is by far the most effective substance that I've tried toward reducing inflammation. It makes eye inflammation pretty much a non-issue, at least as far as I can feel. The strong effect lasts for days after it builds up after a couple of doses. You can read my recent full post about my dosing schedule in the recent glucosamine thread in this section of the forums. It also greatly improves my memory issue. One to two months after I started taking NAG, the article about its life extension effects came out. Given the long action of the effects, I greatly suspect some type of hormesis effect that extends well beyond NAGs direct action while its in my blood. I'm not sure if I'll be taking it in one year, as I'm always wary of emergent side-effects, but right now its the best thing going for my type of inflammation as far as I'm concerned. I have four large boxes full of thousands of dollars in supplements, and this is the most effective singular supplement for me. I did get the flu right after I started taking NAG, though, and the infection hung around in one form or another for about two months. This could be coincidence, or it could be due to a possible immune suppressing effect.
Other stacks/supps that tend to remediate my issues in a more limited manner are CILTEP, Rehmmania (catalpol), Aloe Vera Extract, LDN, and Monolaurin. ALCAR would likely help a lot but I get heart symptoms from it that feel like bacteria overproduction. Perhaps I'll try taking it with Monolaurin. As you can tell from my experience, immune issues and possible resultant bacteria issues are not divorced from issues of long-term inflammation.
Edited by golgi1, 19 April 2014 - 04:32 PM.