176 replies to this topic

[Grandmaster]

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[jack black]

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here you go:

 

Tesla used polyphasic sleeping and he had an eidetic memory(its an information from several articles and books, also he could see how his invention gonna work in his mind with great detail) so there may be something in it.

 

i had to look it up: https://en.wikipedia...olyphasic_sleep

 

 

The term polyphasic sleep is also used by an online community that experiments with alternative sleeping schedules to achieve more time awake each day. However, researchers such as Piotr Woźniak warn that such forms of sleep deprivation are not healthy.^[3] While many claim that polyphasic sleep was widely used by some polymaths and prominent people such as Leonardo da Vinci, Napoleon, and Nikola Tesla, there are few reliable sources supporting that view.^[4]

 

I do remember Kramer using that in one of the Seinfeld episodes, LOL.

[Professionallurker69]

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Sorry to kill your hype GrandMaster, but photographic memory/ editid whatever it's called is not obtainable. You could improve your memory by injecting IGF-1, however it shortens your lifespan. Goood luck

[Grandmaster]

 

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Sorry to kill your hype GrandMaster, but photographic memory/ editid whatever it's called is not obtainable. You could improve your memory by injecting IGF-1, however it shortens your lifespan. Goood luck

 

 

Eidetic and photographic memory are two different things as we figured out in this topic. Photographic memory is fictional thing which hasn't any historical facts or studies behind it(maybe Elisabeth story with dots) and eidetic memory is confirmed to exist and we have several facts connected to it that make this kind of memory very plausible to exist(John von Neumann case, William Sidis, Ferdinand Marcos, Nikola Tesla, Stephen Wiltshire- although its savant case, Arturo Toscanini, Charles Nalder Baeyertz etc..). Also we can also talk about ways to achieve perfect memory with mnemonics or nootropics and not only visual but for example echoic(Glazunov, Rachmaninov, many great composers) and other types of memory.

[Professionallurker69]

 

 

Refresh

Sorry to kill your hype GrandMaster, but photographic memory/ editid whatever it's called is not obtainable. You could improve your memory by injecting IGF-1, however it shortens your lifespan. Goood luck

 

 

Eidetic and photographic memory are two different things as we figured out in this topic. Photographic memory is fictional thing which hasn't any historical facts or studies behind it(maybe Elisabeth story with dots) and eidetic memory is confirmed to exist and we have several facts connected to it that make this kind of memory very plausible to exist(John von Neumann case, William Sidis, Ferdinand Marcos, Nikola Tesla, Stephen Wiltshire- although its savant case, Arturo Toscanini, Charles Nalder Baeyertz etc..). Also we can also talk about ways to achieve perfect memory with mnemonics or nootropics and not only visual but for example echoic(Glazunov, Rachmaninov, many great composers) and other types of memory.

 

 

I was referring to both, sorry for not being clear enough. Both photographic and eidetic memory cannot be achieved through supplementation. PM if you want evidence. 

[Grandmaster]

 

 

 

Refresh

Sorry to kill your hype GrandMaster, but photographic memory/ editid whatever it's called is not obtainable. You could improve your memory by injecting IGF-1, however it shortens your lifespan. Goood luck

 

 

Eidetic and photographic memory are two different things as we figured out in this topic. Photographic memory is fictional thing which hasn't any historical facts or studies behind it(maybe Elisabeth story with dots) and eidetic memory is confirmed to exist and we have several facts connected to it that make this kind of memory very plausible to exist(John von Neumann case, William Sidis, Ferdinand Marcos, Nikola Tesla, Stephen Wiltshire- although its savant case, Arturo Toscanini, Charles Nalder Baeyertz etc..). Also we can also talk about ways to achieve perfect memory with mnemonics or nootropics and not only visual but for example echoic(Glazunov, Rachmaninov, many great composers) and other types of memory.

 

 

I was referring to both, sorry for not being clear enough. Both photographic and eidetic memory cannot be achieved through supplementation. PM if you want evidence. 

 

We are not only talking about getting eidetic memory through use of nootropics but also training with techinques(fairy) or mnemonics.

 

EDIT: How can you write things like that anyway? Have you tried every nootropic and procognitive substance that exist to say such things and be sure about it? I doubt you tried permille of it like most human beings so rethink that.

Edited by Grandmaster, 18 July 2017 - 10:17 AM.

[Grandmaster]

Refresh since 10 days passed and ofc i haven't got any evidence from professionallurker as i thought.

[Izan]

key to a super powerful memory unlocked

 

 

http://www.longecity...-to-alzheimers/

[Grandmaster]

Anyawy. eversing memory loss =/= eidetic memory. I have also heard about that c16 PKR Inhibitor may give perfect memory but there is quiet about it know so i dont think that 15000 dollars per gram substance have worked for anyone in procognitive way.

[Advocatus Diaboli]

It seems that if lost memories can be restored, then one's memory is perfect, no? So, why wouldn't reversing memory loss result in a Von Neumann-type memory?

 

“It’s a poor sort of memory that only works backwards" From "Through the looking Glass".

 

 Confabulation not allowed.

Edited by Advocatus Diaboli, 22 September 2017 - 11:24 PM.

[Grandmaster]

It seems that if lost memories can be restored, then one's memory is perfect, no? So, why wouldn't reversing memory loss result in a Von Neumann-type memory?

 

“It’s a poor sort of memory that only works backwards" From "Through the looking Glass".

 

 Confabulation not allowed.

 

He had eidetic memory but not in all fields: he memorized over 50 history books as a child and then at univeristy he destroyed professor with byzantine knowledge, memorized books like Tales of Two Cities and quoted em back verbatim, memorized d'Arc process texts but couldnt tell where he had glasses in house where he lived for if i remember good for 7 years etc. So it was possibly perfect "classical" memory and maybe echoic but not visual and only for things that he were interested in and was focused on them as far i can say. Even Stan Ulam wrote in book that John Von Neumann was echoic memory person.

 

What can you restore if your normal memory would make memorizing large amouts of informations impossible? Its not an eidetic memory in this case.

[Advocatus Diaboli]

"What can you restore if your normal memory would make memorizing large amouts of informations impossible?"

 

Why large amounts? Just remember those amounts of information that are conformable with one's current memory capacity. Once it's determined that the information has been "forgotten" then "restore" it. Although, it might be somewhat of a bother making the determination that memories have been forgotten and then having to continually restore them (which may be totally impractical).

[Grandmaster]

"What can you restore if your normal memory would make memorizing large amouts of informations impossible?"

 

Why large amounts? Just remember those amounts of information that are conformable with one's current memory capacity. Once it's determined that the information has been "forgotten" then "restore" it. Although, it might be somewhat of a bother making the determination that memories have been forgotten and then having to continually restore them (which may be totally impractical).

 

We are trying here as you can see in first post crack secret of memorizing unbelievably large amounts of informations like whole pages of text or books at single glance(eidetic visual memory) or just by normal reading(classical perfect memory like JvN or Euler).

[medievil]

I'm positive this is possible, at least with a extensive stack of the most powerful nootropics like cerebrolysin perhaps even stone added, semaxetc, achieving this with a couple of the more weak nootropics is wishfull thinking.

[Grandmaster]

Refresh, “Never give in. Never give in. Never, never, never, never—in nothing, great or small, large or petty—never give in" W. Churchill

[Grandmaster]

Refresh, almost forgot about this topic

Edited by Grandmaster, 18 January 2018 - 01:55 PM.

[jack black]

i noticed that when i feel better and relaxed, my memory is worse. when i feel miserable, my memory is better.

my memory is shit overall and getting worse with aging. another thing i noticed, some of the recalled memories are distorted and untrue. if you discover a memory miracle, let me know.

[Grandmaster]

i noticed that when i feel better and relaxed, my memory is worse. when i feel miserable, my memory is better.

my memory is shit overall and getting worse with aging. another thing i noticed, some of the recalled memories are distorted and untrue. if you discover a memory miracle, let me know.

 

When i feel great i also notice that my creativity and verbal fluency is at normal good level but memory is sometimes working better when i feel less mental clearity. Maybe its connected in some way to the fact that savants for example like Kim Peek had eidetic memory but were retarded in social skills and had low IQ. Small children often have eidetic memory because brain is not interpretating what eyes see and save all info like a snapshot without analysis.

 

Huperzine A, galantamine and phosphatidylserine may be useful to improve memory when brain and memory is getting worse with aging.

[gar]

I have actually tried the military method and i dont have great progress with it. Could you please give me some recommendations on how to approach it. Some flashes are very clear and sometimes the letters are blurry. In two weeks this overall did not change. I even switched to a document with big letters (36) but there is still no progress measurable.

Has anybody else tried it?

[Mr Matsubayashi]

I found the following has made meaningful improvements to my cognition, figured i'd post it here as a bump. 

 

1) Eating whole food plant based. Dairy, Meat, Refined sugar are honestly no good. 

           All aspects of mental and physical health improved for me

2) Correcting vitamin D status with 10,000 units/day, then stabilised with 5000 units/day.  https://www.ncbi.nlm...les/PMC5541280/

           Sleep improved. Helped me to relax. VitD has heaps of functions in your body and most people are very deficient. This builds up in your body and is low maintenance.

3) Taking a 20mg lutein xeanthine supplement every other day https://www.ncbi.nlm...les/PMC5707718/

           Some small noticeable improvement in memory. This builds up in your body and is low maintenance. 

4) Before going to bed, mixing 400mg of powdered phosphatidylserine with two teaspoons of algae based omega 3 

            Makes me confident, and cool as a cucumber the next day. Also improves cognition and sleep. This is expensive at $80/month.  

5) 30mg of Uridine salts sublingual in the morning.  

            Improves mental clarity and helps with motivation. If I take the suggested 250mg orally I feel tired. 

 

I plan to build upon this with some of the compounds identified earlier to see if I can make something magical happen. 

Edited by Mr Matsubayashi, 17 May 2019 - 06:16 AM.

[Mr Matsubayashi]

I have added a few drops of turmeric oil CO2 extracted sublingual in the morning. I thought about adding this in response to a post I found where curcumin and berberine dramatically improved someones memory on reddit. The CO2 extract of turmeric is rich in ar-turmerone (about 30%) which has been found to increase NCS proliferation in rats and felt more interesting to trial than curcumin capsules i've tried in the past to little effect. The effect of the sublingual tumeric oil in concert with what i'm doing above results in focus and energy that lasts all day until I go to sleep, something in common with the reddit post. I have been ridiculously productive and I hope it is sustainable. I'll start playing around with HCL berberine soon. 

 

If you try dissolving the phosphatidylserine in Omega 3 trick I have tried a few products and found the best effect and taste with the following;

https://www.jarrow.com/product/556/PS

https://www.nutrasea...omega-3-plant-1

 

This is the tumeric oil product i'm using. Its the only one i've tried. 

https://www.auracaci...ract-0-5-fl-oz/

 

I prefer the nootropics depot powder uridine because it has no fillers unlike capsule powder. 

 

For the other components i'd use whatever is convenient. 

 

https://www.reddit.c...tm_medium=web2x

 

https://www.ncbi.nlm...pubmed/25928248

https://www.ncbi.nlm...pubmed/25688994

 

 

[Keizo]

When i feel great i also notice that my creativity and verbal fluency is at normal good level but memory is sometimes working better when i feel less mental clearity. Maybe its connected in some way to the fact that savants for example like Kim Peek had eidetic memory but were retarded in social skills and had low IQ. Small children often have eidetic memory because brain is not interpretating what eyes see and save all info like a snapshot without analysis.

 

Huperzine A, galantamine and phosphatidylserine may be useful to improve memory when brain and memory is getting worse with aging.

My spontaneous thoughts when on the rare occasion having a low amount of alcohol or benzodiazepine in my system (especially benzodiazepine), is that "this is how normal people function". It seems to improve fluidity of speech and engagement in the world at low enough dosages, but the effects on memory to me are always super apparent and mildly negative, as well as making one rather dumb (but this is not outwardly apparent at these dosages I'm talking about). I have also noticed some substances (probably most notably d-amphetamine, methylphenidate and Cerebrolysin) make me at times feel a bit depressed or negative, but nevertheless make me perform well during those times best of my telling.

 

One sort of stereotype is that introverted people can spend more of their time thinking and analyzing, whereas extroverts are spending more time just regurgitating their ideas or seeing how they work in the real world. I guess perhaps some peculiar types of introverts (whatever that means) are like those "small children" you describe, they are more stuck in their heads and so they can more accurately remember things (but this might include moods and social interactions and their details as well). I want to say that there isn't necessarily a difference between being able to perfectly analyze and recall a social situation as a passive observer versus perfectly analyze and recall  10 pages of a chemistry book. Both are complicated things that can require very similar types of brain power. "Social skills" don't necessarily relate to understanding, but rather performance and sort of like muscle memory.  I think it quite possibly some people with diagnosed autism score low on IQ tests because they can't perform, rather than them not necessarily being able to comprehend. I'm not just talking anxiety I'm talking all kinds of things that are sort of like muscle memory or gut instincts that for most people, they just are able to get into that mode and that enables them to use their brainpower to a significant degree in a situation.

 

I know one person who alleged to be diagnosed with Autism and certified retarded in a certain US state back in the day, but years later he seems like a rather normal person after lots of tutoring to help him read and speak properly, altho I might wrongfully conflate his obscure interests and somewhat high level of verbal fluency with actually being able to get above 70 or whatever on an IQ test.

- - - -

 

I don't like to try a bunch of compounds anymore, but as far as really amazing recall of pages of books, the only thing I can say possibly gave me that ( and various flashbacks here and there while walking and thinking about stuff) is PRL-853. But there is to me one big problem with this compound and it's that it makes me really really tired after using it for a period and then stopping (even just 10mg every morning), at least that was the case the weeks I took it years ago. Methylphenidate or even d-amphetamine never gives me this tiredness, PRL-853 after a few weeks on about 10mg a day I felt absolutely exhausted in the morning after a good nights sleep, until the next dose came to work. Fasoracetam is interesting to me cause it coincided with me getting some great results at chemistry courses, but I think that's more of a general attention enhancer (unlike any I've tried, much more effective than prescription stimulants to me for studying).

 

I will try PRL 853 again at some point, probably.

Edited by Keizo, 20 June 2019 - 12:49 PM.

[BlueCloud]

I’ve actually cracked the formula for eidetic memory yesterday, and it’s...it’s...uh...mmm...wait, its going to come back to me in a sec....it’s ...damn i think i forgot it...

[Mr Matsubayashi]

I’ve actually cracked the formula for eidetic memory yesterday, and it’s...it’s...uh...mmm...wait, its going to come back to me in a sec....it’s ...damn i think i forgot it...

 

Solid LOL. 

 

I have been off everything for about a week now and I can confirm there is no tolerance and that some of the effects are seemingly persistent. 

 

I did try berberine HCL 350mg but found myself nauseous, the same with hydergine. Both seemed to put me slightly backwards cognitively. I'll experiment some more. 

[Mr Matsubayashi]

A new addition to what i'm doing is melatonin at night. Pharmacological concentrations are shown to increase NCS differentiation and integration significantly. I think this has been cycling well with the ar-turmerone increasing proliferation during the day and melatonin differentiation and integration at night. I have also started consistently drinking coffee in the morning, I found in my previously experience my day long productivity and extreme focus as connected to my morning coffee. It doesn't need to be much in my experience, i'm just using a single work provided coffee pod. It is well documented in anecdata the uridine enhances coffee, and I have read elsewhere that new neurons are more sensitive to all catecholamines. It could also be that ar-turmerone is a MAOI. 

 

https://www.ncbi.nlm...pubmed/28423196

https://www.ncbi.nlm...les/PMC3840684/

 

Swinging this back around to the focus of this thread, my memory of past events, places, short term problem solving memory and future planning are all significantly improved from what they were. There is seemingly no tolerance or burnout from what i'm doing with effects about 60% persistent on days I do nothing.  

 

A side effect is that in the morning i have low motivation to get out of bed. It might be a melatonin hangover or something to do with new neurons. This is replaced with focus after getting out of bed, even before the coffee. 

 

For context and to help other experimenters, i'm a 30yo male, homozygous COMT mutant, with a heterozygous MTHFR mutation. I don't eat meat, limited dairy. I used to suffer from insomnia. The only other thing I haven't mentioned thus far is that I take B12 once a week. 

Edited by Mr Matsubayashi, 21 July 2019 - 11:26 AM.

[Mr Matsubayashi]

Ar-Turmerone Calculations

 

Please correct these calculations if you know what you’re doing, because I don’t.

 

The oil extract varies between 21% to 46% Ar-Turmerone depending on which part of the plant is used and the extraction method. It can be concentrated further.

https://pdfs.semanti...636ebd2f1ba.pdf

https://www.research...Curcuma_longa_L

 

The vitro study found peak effects at 6.25ug/ml and negative effects beyond 12.5ug/ml. The vitro exposure was 10 days.

https://stemcellres....10.1186/scrt500

 

This mouse study injected mice with 50mg/kg Ar-Turmerone and found levels in the brain peaked at 210 ng/g and were still above 200ng/g after 24 hours. Ar-Turmerone crosses the blood brain barrier, it is a small lipid.

https://journals.plo...al.pone.0081634

 

The oral bio-availability of Ar-Turmerone is 13%. This is commented on in the safety study at the end, but without reference.

 

Assuming density of brain is about the same as the density of body

Assuming density of ar-turmerone = turmeric oil 960mg/ml = water = 1000 mg/ml.

200ng/g = 200ug/kg

50mg/kg = 50000ug/kg

200/50000 = 0.4% of injected concentration is available in a mouse brain.

Mouse dose injected for optimal brain concentration.

6.25ug/ml / 0.4% = 1562.5ug/ml = 1562.5 ug/g = 1.562g/kg

 

Converting for human dose Injected

https://www.ncbi.nlm...les/PMC4804402/

 

1.562g/kg / 6.2 = 0.2519g/kg

Factoring in oral bio-availability

0.2519g/kg / 0.13 = 1.938g/kg

Factoring in fraction ar-turmerone in commercial extracts

1.938g/kg / 0.3 = 6.459 g/kg = 6.459 ml/kg

Assuming human (Mr Matsubayashi) weight 80kg

6.459 ml/kg * 80kg = 516ml lol

 

If bio-accumulation is factored in, oral daily dose is: 25.8ml.

 

Because of the high oral dose required sublingual administration is recommended. It seems mice have slow metabolism of the oil, assuming the same applies to humans successive days of administration may get brain concentrations to therapeutic levels.

 

How do the effects of neurogenesis compare to its MAOI activity?

https://www.ncbi.nlm...les/PMC3840684/

 

5mg/kg oral Ar-Turmerone / daily over a week. Assuming bio accumulation and bioavailability as defined above, estimated effective injected dose is the same at: 4.322mg/kg. Reduced MAO activity by 17.4% on average. Its clear that Ar-Turmerone is a stronger MOAI. Its also clear that its bio-available and passes the BBB. As a side note, I tried L-tryptophan and found myself periodically twitching after, a hallmark of L-tryptophan with MAOI. This could be exacerbated by being a COMT mutant, I had not tried L-tryptophan prior.

 

Based on this evidence I must conclude that the effects I have noticed are due to Ar-turmerones MAOI activity and slow clearance, and not some magical neurogenesis effects. In saying this, Ar-turmerone has demonstrated anti-inflammatory effects and reduces corticosterone. It appears to be helpful in many conditions.

 

My estimated total dose so far is 10ml, taken sublingually over 2 months. Rough calculations of my steady state brain concentration assuming improved bio-avail via sublingual comes to:  0.083ug/ml. Equivalent mouse dose w.r.t metabolism: 0.516ug/ml. At these concentrations based on the study above I might expect some tiny neurogenesis benefit.

 

An overall good summary on Ar-Turmerone and review of its safety, copied verbatim:

https://scindeks-cla...2241535003S.pdf

 

Some studies reported that turmeric oil is safe even at high dose. Food and Drug Administration (FDA) approved turmeric oil usage as food additive and is listed as Generally Recognized As Safe (GRAS), while the FDAs GRAS list does not include the dosage of turmeric oil. Turmeric oil is usually used in aroma therapy and the recommended dose is 1–2 drops/day. Acute administration of turmeric oil was done as single dose up to 5 g of turmeric oil per kg body weight and subchronic toxicity study for thirteen weeks was done by daily oral administration of turmeric oil at doses 0.1, 0.25 and 0.5 g/kg body weight in wistar rats. There were not found any mortality, adverse clinical signs or changes in body weight, water and food consumption during acute as well as subchronic toxicity studies. Indicators of hepatic function such as aspartate aminotransferase, alanine amino transferase and alkaline phosphatase were unchanged in treated animals compared to untreated animals. Oral administration of turmeric oil for 13 weeks did not alter total cholesterol, triglycerides, and markers of renal function, serum electrolyte parameters and histopathology of tissues. Turmeric oil did not produce any mutagenicity to Salmonella typhimurium TA-98, TA-100, TA-102 and TA1535 with or without metabolic activation. Administration of turmeric oil to rats (1 g/kg b.wt.) for 14 days did not produce any chromosome aberration or micronuclei in rat bone marrow cells and did not produce any DNA damage as seen by comet assay confirming the non toxicity of turmeric oil. Anti-arthritic evaluation of turmeric oil in mice was carried out at doses of 560 mg/kg body weight [7]. Turmeric oil (0.1–3 mg/plate) did not produce any revertants during Ames test, indicating that there was no significant dose related mutagenicity of the turmeric oil either with or without metabolic activation. Genotoxic substances are potentially known to be mutagenic or carcinogenic. Exposure of cells to genotoxic substances damage chromosomes of the mitotic spindle leading to the formation of micronuclei. Genotoxic studies of turmeric oil such as micronuclei formation, chromosomal aberrations and genomic DNA damage analysis by comet assay have revealed that there was no genotoxic effect after 2 weeks oral administration of 1 g/kg body weight turmeric oil [38].

 

 

 

[BieraK]

What I have found gives me an spatial eidetic memory Is a 5% Huperzine extract. It Is Brown in colour not the white one.
The white 1% Huperzine that is generally sold is 99% Huperzine A mixed with some filler to make 10 mg of that powder equivalent to 100 mcg of Huperzine A. Huperzine 5% brown maintains other components of the plant that have a psychoactive effect. For example, 5% brown Huperzine produces cerebral vasodilation and relaxes the muscles, 1% white Huperzine does not produce that. On the other hand, I can take high doses of Huperzine 5% without problems. According to this study, 1 mg Huperzine A releases Dopamine and Norepinephrine in the prefrontal cortex. In my experience the ideal state of memory enhancement is high acetylcholine, high dopamine, increased vasodilation and blood flow to the brain. Ideally, an increase in AMPA transmission and a reduction in NMDA. Inhibiting PDE4 also helps. IDRA-21/Low dose Sunifiram (0.1 mg since it releases Acetylcholine at the PFC), an NMDA antagonist like memantine or Huperzine+Mag Threonate, a vasodilator an small dose of a stim is the key.

https://pubmed.ncbi....ih.gov/7500384/

Proposed stack:
1) Huperzine 5% 50 mg or the Max dose you could tolerate
2) Methylphenidate ER the lowest effective dose
3) Mitochondrial support: Lipoic Acid, CoQ10, ALCAR, PQQ
4) Vasodilation: What works Soidum Nitrate+Vit C or Beetroot. Citrulline could work also. Huperzine full Spectrum Is a vasodilator also so this depends on the individual
5) Dopamine support: P5P+Tyrosine. Low dose Bromantane could work here also.
6) AMPA/NMDA ratio: Choose what works best for you.
7) PDE4 inhibition: Ibudilast / Quercetin / Artichoke Extract

Edited by BieraK, 28 April 2024 - 04:40 AM.