what happened to this group buy
There is no group buy because it has become clear that we can obtain this compound directly with minimal cost overhead.
Finally, after almost a year, I got back on betaBGF last week. This time, I decided to pay for dry ice shipping to see if the effects were any different. As soon as it arrived, I make a fresh nasal spray batch, and dripped in about 4 ug.
Bear in mind, this is the first dose I've had since my surgery. So it's interesting that about half an hour later, the area between my chin and my lower lip started feeling cold, as though I had applied toothpaste to the area. This area had lost much of its sensation as a result of the surgery, and has only partially recovered, so this sort of response makes some sense. I may have dripped some of the nasal spray on it by accident during the dosing process.
But about 20 minutes later still, while I was sitting down working on other things, I started to feel the same "toothpaste" sensation on the roof my mouth toward the front. This is the other major area which had lost much of its sensation as a surgical side effect. It got severe enough to become an annoyance, and only subsided after a couple of hours. Perhaps it occurred due to nasal drainage, or perhaps both symptoms were due to betaNGF which had entered the blood stream and migrated to the affected sites. Either way, especially in the second case, the effect was unmistakable.
In the several days since, on every day but one, I applied a single spray in each nostril, rather than dripping, in exactly the same manner of application as normal nasal spray. The downside of this practice is obviously that the olfactory bulb gets much less exposure than via the drip method, so if it works at all, it must be mostly due to diffusion into the tissues near the brain and the circulation in general. Even if we assume that it cannot cross the BBB, it can definitely cross in places where that vascular network is ruptured. With enough microvascular damage, for instance, it ought to be able to enter the brain easily. (Having said that, I think the data shows that it crosses the BBB everywhere, as previously discussed.)
I estimate that the switch in technique has knocked down my dose by roughly a factor of 10. Since doing so, I have not yet experienced a repeat of the toothpaste sensation. However, I have once again started to experience very vivid dreaming. As before, it's not merely clear and realistic. It's logical, in the sense that the laws of physics seem to be followed just as in the real world, and people behave in the way that one would expect in a modern society. For example, I dreamed of a place where I drove somewhere to get something, then drove back later. On my return, I took the opposite side of the same road, and had to make a U turn back to my destination, in a manner consistent with real road networks; these are not "LSD" episodes with flying monkeys and rainbow colored horses. Suffice to say, though, that none of this means that your dreams will be uplifting or reassuring. Mine seem to have been quite the opposite for the most part.
This is not to say that betaNGF somehow causes panic or anxiety; the science suggests very much the opposite. Even in my sober and at times terrifying dreams, I would not characterize my reactions as such. And while awake, I've noticed that several minutes after a spray dose, my whole body seems to slow down and relax with no effort on my part. It's a subtle effect, though, which might well be placebo. I'm generally very calm as it is, so I'm not the ideal candidate to perform such a test. It would be interesting to see what more anxious people experience in this regard, although in good faith I cannot recommend that anyone copy my uncontrolled human experiment.
In sum, these observations strengthen my hypothesis that "nerve growth factor" is a misnomer. It should be called "neuron stem cell activating factor", as neuron growth is merely a secondary and very longterm consequence of its actions. I should add that the dry ice didn't seem to enhance the magnitude of the effect, which reinforces my suspicion that this substance is more stable than the documentation would lead us to believe.
At this point, after months on ashitaba chalcone, I would say that betaNGF has a more immediate and obvious impact on brain function. It may just be that chalcone acts over a long period of time, or maybe its effects are quite simply too subtle, apart from its obvious and rapid appetite suppression.
Edited by resveratrol_guy, 21 June 2016 - 02:08 PM.