3 replies to this topic

[ironfistx]

I got some manganeses supplements that are 10mg or 500% and I picked them cuz I needed something small to put my order over a total to get a discount. They are Albion made. According to webmd taking over 11mg per day can be dangerous. Is this a supplement that is good for normal use or is it only for individual conditions? Should I exchange it?

[datrat]

Our bodies do use manganese to make dopamine, but we probably get all we need from a normal diet. I got a really nice placebo effect from 10 mg of manganese for one night, after that nothing at all. I don't know that there is a definitive answer on the risks of taking 10 mg daily. Maybe if you want to try it, but be safe, just one a week. Otherwise limited benefits + potential risk = probably return it.

[blood]

I don't believe manganese supplements should be taken by people.

Reasons:
1) There are no documented cases of human manganese deficiency "in the wild". (Manganese deficiency has only ever been produced in humans via feeding a highly purified, elemental diet, i.e., laboratory conditions.) So, what is the justification for supplementation?
2) non-food bound manganese, such as the manganese dissolved in drinking water in certain municipalities, is highly bioavailable (more bioavailable than manganese found in food), and is able to bypasses/defeat bodily mechanisms which have evolved to prevent absorption of excess manganese. Consumption of very small amounts of waterborne manganese - less than 1 mg/ day - have been linked (observational studies) to nasty cognitive outcomes, e.g., substantial reductions in IQ in children.
3) My fear is that the manganese found in dietary supplements is more bioavailable than that in food (just as supplemental copper and copper dissolved in drinking water is more bioavailable than food bound copper.) (Note: high consumption of copper from drinking water and supplements is linked to accelerated cognitive decline). Manganese is a potent neurotoxin in 'excess'. There are no modern studies seeking to evaluate the safety of manganese supplements - which is a travesty because manganese is routinely included in multivitamins. My choice is to *avoid* until supplemental manganese has been shown safe.

Edited by blood, 05 August 2014 - 08:30 AM.

[StevesPetRat]

Manganese has MAOi properties and is important for connective tissue health. I would not supplement more than say 5 mg daily though. Therapeutic level is pretty close to toxicity threshold.

Maybe take one of those 2 or 3 times a week at most.