70 replies to this topic

[Area-1255]

superiorpeptide.com claims to have liquid tadalafil drops, lostfalco has recommended this website

I've heard good things about them as well, but some people don't like liquids.

[magta39]

true...I have not tried it yet....I suppose liquids are more prone to bacterial contamination

[Area-1255]

true...I have not tried it yet....I suppose liquids are more prone to bacterial contamination

I think it's more a question of measuring it out and whether it's potency gets fluctuated in the mixture. 

Sublingual tablets are pretty good.

[magta39]

yes that would be ideal...any suggestions where to get sublingual tadalafil tabs?

[Area-1255]

yes that would be ideal...any suggestions where to get sublingual tadalafil tabs?

http://www.internati...afil-xtenda.htm

[Area-1255]

But as far as regular tablet, either IDM or all saints.

[nowayout]

 

 

Thanks for the feedback, yes , if you have the means (or the $$$), every man should take a low-dose of Cialis to enhance PWO's or for pump. For average men with high test levels, only 2.5 mg - 5mg / day is all you need. 

 

It is astronomically expensive, but nobody needs to pay those prices.  The Cipla generic tadalafil is sold for about a twentieth of the price of the brand name Cialis.  

 

Yeah but there's a lot of scams out there too, that's part of the issue...you know with the generic's and manufacturers from different countries. Re-sellers and what not, they can manipulate the goods and then offer it at a fraction of the original price.

 

I am sure there are lots of scams.

 

However, most people I know have done fine with the Cipla brand from places like Alldaychemist.  Cipla is a good company and various other drugs they manufacture are sold routinely in U.S. and E.U. pharmacies, just not tadalafil and that only for patent reasons.  However, I have had no problems importing for personal use. 

 

[Area-1255]

 

 

 

Thanks for the feedback, yes , if you have the means (or the $$$), every man should take a low-dose of Cialis to enhance PWO's or for pump. For average men with high test levels, only 2.5 mg - 5mg / day is all you need. 

 

It is astronomically expensive, but nobody needs to pay those prices.  The Cipla generic tadalafil is sold for about a twentieth of the price of the brand name Cialis.  

 

Yeah but there's a lot of scams out there too, that's part of the issue...you know with the generic's and manufacturers from different countries. Re-sellers and what not, they can manipulate the goods and then offer it at a fraction of the original price.

 

I am sure there are lots of scams.

 

However, most people I know have done fine with the Cipla brand from places like Alldaychemist.  Cipla is a good company and various other drugs they manufacture are sold routinely in U.S. and E.U. pharmacies, just not tadalafil and that only for patent reasons.  However, I have had no problems importing for personal use. 

 

 

AlldayChemist can be hit or miss, some people report broken pills or messed up packaging...but I think for the most part, they are pretty reliable.

[Junk Master]

My rat is currently experimenting with low doses of the peptide IPT-141.  I'll let you know how it goes.

 

[Area-1255]

My rat is currently experimenting with low doses of the peptide IPT-141.  I'll let you know how it goes.

I tried that from CEM, was interesting...although at higher doses, I felt almost , well...weirdly euphoric...and when I took a nap I would have weird sleep paralysis type symptoms...but that was only at higher doses. >3mg

It did have a ridiculously strong libidogenic effect, though. 

It will certainly amplify an already present sexual addiction.

You'll be picking up an escort every other night or banging your girl 20x a day. 

Whatever applies or comes first.   

[Bateau]

 

Has any one considered Red Kwao krua root extracts or as many call it butea superba root? Many Asian studies have shown results very impressive results compaired to big pharma PDE5 drugs. Eastern Medicine literature is hidden from us by the east but it doesn't help the FDA discrediting every translated one. What do you guys think of butea superba??

Yes ; it's strong stuff. It mainly prevents the hydrolyzation/degradation of cAMP, though.

With that being said, it had some powerful anti-depressant effects, comparable to rolipram; very euphoric!!

 

 

Are you saying you've tried Rolipram?
 

[Area-1255]

 

 

Has any one considered Red Kwao krua root extracts or as many call it butea superba root? Many Asian studies have shown results very impressive results compaired to big pharma PDE5 drugs. Eastern Medicine literature is hidden from us by the east but it doesn't help the FDA discrediting every translated one. What do you guys think of butea superba??

Yes ; it's strong stuff. It mainly prevents the hydrolyzation/degradation of cAMP, though.

With that being said, it had some powerful anti-depressant effects, comparable to rolipram; very euphoric!!

 

 

Are you saying you've tried Rolipram?
 

 

That I have.

[Bateau]

 

 

Are you saying you've tried Rolipram?
 

That I have.

 

 

Care to comment more on that?

 

Where did you get it?

How much did you take?

Nausea?

Perceived benefits?

Tested Benefits?

Repeated dosing?

etc.
 

[Junk Master]

Good thread!

[Area-1255]

Good thread!

My aim is to provide a broad collection of information and studies; to provide new insight into optimization of all aspects of health. 

Edited by Area-1255, 24 April 2015 - 11:09 PM.

[Area-1255]

 

 

 

Are you saying you've tried Rolipram?
 

That I have.

 

 

Care to comment more on that?

 

Where did you get it?

How much did you take?

Nausea?

Perceived benefits?

Tested Benefits?

Repeated dosing?

etc.
 

 

It was a sample from a small group buy a long while back. 

It was about 125 mg. 

Mild nausea.

Benefits were increased memory function and creative drive, and a noticeable sensory euphoria. 

I took it sporatically , three times in a week, that was it.

 

Dipyridamole is a non-selective cAMP PDE-inhibitor, 28 bucks for pretty much a month supply --> https://www.1napsgear.org/product_info.php?ref=2522&products_id=416

 

Check out this thread here on it. Studies included, seems it could skyrocket test levels.

http://www.mindandmuscle.net/forum/25503-pde-8-pdes-inhibitors-super-testosterone-levels-recovery

[Area-1255]

Butea superba definitely seems interesting, here's a whole write-up on it. 

http://thaiherbinfo.com/herb/Butea%20superba%20_Downloads/J.%20Sci.%20Res.%20Chula.%20Univ.,%20Vol.%2025,%20No.1%20(2000).pdf

http://examine.com/s.../Butea superba/

http://www.hindawi.c...am/2013/874894/

http://www.researchg...ile_dysfunction

 

 

A flavonoid (3, 7, 3'-Trihydroxy-4'-methoxyflavone) (1) and a flavonoid glycoside (3, 3'-dihydroxy-4'-methoxyflavone-7-O-β-D-glucopyranoside) (2) were isolated from the tuber root of Butea superba Roxb. The structures were determined on the basis of spectral analysis, including 2D-NMR techniques. These compounds show higher inhibitory effects on cAMP phosphodiesterase than caffeine and theophylline.

 

 

[Area-1255]

Interestingly, heavy/moderate exercise where heavy weights are involved - may be the ultimate augmentor / enhancer of PDE-5I's or nitric oxide boosters...as eventually heavy exercise actually dampens the alpha-adrenergic system leading to more vasodilation. Aerobic exercise and running have powerful influence on neurohormones and N.O as well through the pathways mentioned below.

 

 

J Appl Physiol (1985). 2001 Jan;90(1):172-8.

Exercise attenuates alpha-adrenergic-receptor responsiveness in skeletal muscle vasculature.

Buckwalter JB1, Naik JS, Valic Z, Clifford PS.

Author information

 

Abstract

Attenuation of sympathetic vasoconstriction (sympatholysis) in working muscles during dynamic exercise is controversial. A potential mechanism is a reduction in alpha-adrenergic-receptor responsiveness. The purpose of this study was to examine alpha(1)- and alpha(2)-adrenergic-receptor-mediated vasoconstriction in resting and exercising skeletal muscle using intra-arterial infusions of selective agonists. Thirteen mongrel dogs were instrumented chronically with flow probes on the external iliac arteries of both hindlimbs and a catheter in one femoral artery. The selective alpha(1)-adrenergic agonist (phenylephrine) or the selective alpha(2)-adrenergic agonist (clonidine) was infused as a bolus into the femoral artery catheter at rest and during mild and heavy exercise. Intra-arterial infusions of phenylephrine elicited reductions in vascular conductance of 76 +/- 4, 71 +/- 5, and 31 +/- 2% at rest, 3 miles/h, and 6 miles/h and 10% grade, respectively. Intra-arterial clonidine reduced vascular conductance by 81 +/- 5, 49 +/- 4, and 14 +/- 2%, respectively. The response to intra-arterial infusion of clonidine was unaffected by surgical sympathetic denervation. Agonist infusion did not affect either systemic blood pressure, heart rate, or blood flow in the contralateral iliac artery. alpha(1)-Adrenergic-receptor responsiveness was attenuated during heavy exercise. In contrast, alpha(2)-adrenergic-receptor responsiveness was attenuated even at a mild exercise intensity. These results suggest that the mechanism of exercise sympatholysis may involve reductions in postsynaptic alpha-adrenergic-receptor responsiveness.

PMID:   11133908   [PubMed - indexed for MEDLINE]    Free full text

 

J Hypertens. 2013 May;31(5):916-26. doi: 10.1097/HJH.0b013e32835f749c.

Aerobic exercise training increases neuronal nitric oxide release and bioavailability and decreases noradrenaline release in mesenteric artery from spontaneously hypertensive rats.

Blanco-Rivero J1, Roque FR, Sastre E, Caracuel L, Couto GK, Avendaño MS, Paula SM, Rossoni LV, Salaices M, Balfagón G.

Author information

 

Abstract

OBJECTIVE:

To study the effect of aerobic exercise training on sympathetic, nitrergic and sensory innervation function in superior mesenteric artery from spontaneously hypertensive rats (SHRs).

METHODS:

De-endothelized vascular rings from sedentary and trained SHRs (treadmill 12 weeks) were used. Vasomotor responses to electrical field stimulation (EFS), noradrenaline, nitric oxide donor DEA-NO and calcitonin gene-related peptide (CGRP) were studied. Neuronal nitric oxide synthase (nNOS) expression and nitric oxide, superoxide anions (O(2.-)), noradrenaline and CGRP levels were also determined.

RESULTS:

Aerobic exercise training decreased vasoconstrictor response to EFS but increased noradrenaline response. Phentolamine decreased while N(ω)-nitro-(L)-arginine methyl ester ((L)-NAME) increased the response to EFS; the effect of both drugs was greater in trained animals. Training also decreased noradrenaline release and O(2.-) production and increased nNOS expression, nitric oxide release and the vasodilator response to DEA-NO. The O(2.-) scavenger tempol increased DEA-NO-induced vasodilation only in sedentary rats. The EFS-induced contraction was increased to a similar extent in both experimental groups by preincubation with CGRP (8-37). CGRP release and vasodilator response were not modified by training.

CONCLUSION:

Aerobic exercise training decreases contractile response to EFS in mesenteric artery from SHRs. This effect is the net result of decreased noradrenaline release, increased sensitivity to the vasoconstrictive effects of noradrenaline and increased neuronal nitric oxide release and bioavailability. These modifications might contribute to the beneficial effects of aerobic exercise training on blood pressure.

PMID:   23429663   [PubMed - indexed for MEDLINE]

 

Edited by Area-1255, 25 April 2015 - 02:59 PM.

[Area-1255]

This thread has really evolved.

[AMx Workshop]

lmao

[magta39]

I always thought lifting heavier weights might raise my blood pressure....maybe that's not the case.  On another note I will try to get some tadalafil when I go to the Philipines this summer

[Area-1255]

I always thought lifting heavier weights might raise my blood pressure....maybe that's not the case.  On another note I will try to get some tadalafil when I go to the Philipines this summer

At first it might raise BP, depending on body fat, personal sensitivity / threshold,,, and dietary / drug influences. Then it should eventually balance out, I feel that long-term exercise or several days a week gives a persistent vasodilated feeling..sometimes even flushed face. Even without an N.O Product, however, I have a theory that N.O is going to be dependent on general neuronal state..and oxygenation will play a role...many people are deficient in oxygen, so really everyone should be taking garlic and suma extract for oxygenation.

[Area-1255]

Also PDE's are technically regulated by thyroid hormones as well.

[Son of Perdition]

But as far as regular tablet, either IDM or all saints.

all saints is better outta the two.

best tadalafil quality  > RCIS

[Area-1255]

 

But as far as regular tablet, either IDM or all saints.

all saints is better outta the two.

best tadalafil quality  > RCIS

 

All saints is definitely G2G. Been around for a while, too.

[AMx Workshop]

 

 

But as far as regular tablet, either IDM or all saints.

all saints is better outta the two.

best tadalafil quality  > RCIS

 

All saints is definitely G2G. Been around for a while, too.

 

Agreed. I know several people who have had excellent results and no inconsistencies like RCI shops.

[Yunasa]

i know like 12 people who use all saints...excellent company. 150 x better than all day chemist.

[DeadBrain]

all saints is better than adc, but idk if its the best outta ALL sites..might be, haven't tried em all.

Edited by DeadBrain, 28 April 2015 - 12:01 PM.

[Area-1255]

all saints is better than adc, but idk if its the best outta ALL sites..might be, haven't tried em all.

Are you sure, deadBrain? 

[Area-1255]

In all seriousness, yes, I recommend everyone try all saints..definitely the best merchandise.