http://rockstarresea...-klotho-levels/
It turns out that lots of people get their klotho levels increased as a side-effect of taking prescription forms of “activated” vitamin D (VDRAs) for chronic kidney disease (CKD). But there’s no reason to wait until you’re almost dying and need dialysis to start benefiting from this knowledge. Instead, this implies that taking something like 0.25 mcg/day of Calcitriol or 1 mcg/day of Paricalcitol right now for someone without the beneficial KL-VS variant of the KL gene might actually give a huge longevity and IQ boost. The intelligence boost is so large, that if this new study is right and the effects of klotho are at all acute, you should be able to measure it directly with something like quantified mind or perhaps even just raw introspection. Hopefully lots of researchers follows up on the most obvious implications of these two currently unconnected research findings and investigate activated vitamin D as a way to boost longevity and cognition in the 80% of the population lacking functional, klotho producing KL-VS genes.
Would regular oral Vitamin D3 produce the same effects ? After all, people with CKD take "activated" vitamind D because their kidneys cannot build it.