Do you get good anti-inflammatory effects from NA-GHK and NA-GHK-A compared to GHK-Cu?
It's hard to say without systematically eliminating other anti-inflammatories from my regimen, as well as other peptides I'm taking. My specific goals are healing a cartilege injury (meniscus tear) that didn't respond to surgery. I've been through 3 rounds of PRP (injected into the knee) this year specifically to induce local inflammation and healing of the region. These injections have occurred eery 6 months for the past months at 8 week intervals. In between, I have limited activity to walking and weight-lifting for at least 4 weeks before adding in low impact activities like spinning or biking and erging.
What have I learned? It's pretty hard to say. The GHK-Cu complex (from TLR) caused local irritation at the injection site. I went through quite a bit of this (100mg x 20) over the course of the first 4 months. Healing in the knee didn't appear to be either positively or negatively affected, and TBH without any other markers to judge from, I'd say it was money down the drain. The color of the solution was so close to purple that it's hard to believe it's GHK-Cu and not something else (Carnosine-Cu shows purple in solution) and none of the other miracle effects reported by some in this thread were born out.
The NA-GHK and NA-GHK-Amidate from Ceretropic were late additions. I've just finished a 20 day run of each at 10mg/day (NA first, then Amidate) and can't honestly say I noticed any strong anti-inflammatory effects. One piece of possible anecdotal evidence for wound-healing is that I did deeply cut my hand between index finger and thumb during the NA-GHK run and it healed enough that I was able to go back to full activities within a week without stitches. The wound should have been stitched but I waited too long to see the doctor so they could only steri-strip it and keep it dry. It is now fully healed and I can lift weights with that hand with no issues. I heal quickly in general, however, so I'm unconvinced.
I've also consistently been running BPC-157 and TB-500 together with CJC-1295 (w/DAC) and mod GRF-29 together with Ipamorelin for GH release. I started these just before the second round of PRP in my knee, hoping to boost healing. This has had the effect of increasing tendon and ligament pain in both the knee and my left elbow (for no reason I know of) and only a new MRI will tell what's actually going on there. I could be making things much worse for all I know.
If there are any anti-inflammatory effects from adding the NA-GHK and NA-GHK-Amidate, I can't anecdotally attest to them. It's possible that the wound-healing I'm hoping to induce is coming coupled with additional pain in the wouded areas. I can only hope that's the case.
For the Epitalon, Thymalin, and NA-Epitalon runs I'm doing, I did a baseline telomere test from Teloyears and will post before and after results once I get them back.
TLDR; not sure what these GHK complexes are doing, but they don't appear to be significantly anti-inflammatory, nor do they produce any visible results within 20 days. This may be too soon to see.