15 replies to this topic

[ikon2]

No puns please

[treonsverdery]

Argnne as a supplement causes greater amounts of spermidine at mice.

I read a paper https://www.ncbi.nlm.../pubmed/2468644 where they gave mice arginine with lKM512 bacteria as part of a measured produced spermdne experiment.  the url is https://www.ncbi.nlm.../pubmed/2468644

 

when I read the paper I thought that 7 grams of arginine was near the beneficial mouse equivalent that is "

delays senescence in mice"

 srep04548-f5.jpg   200.69KB   1 downloads

 

[mikey]

Alibaba has multiple sources for about a dollar a gram...

 

For instance - 

https://haihangindus...s_124_20_9.html

 

I wonder if anyone has purchased from any of the vendors on Alibaba and then had the spermidine tested to be certain of its quality.

Edited by mikey, 10 May 2016 - 12:33 AM.

[normalizing]

after reading this; http://www.medicalne...cles/317088.php now im interested in who sells spermidine as supplement? i saw only lab grade powders sold in huge quantities for quite hefty prices... any help??

[Darryl]

Eisenberg, 2016. Cardioprotection and lifespan extension by the natural polyamine spermidine. Nature medicine, 22(12), pp.1428-1438.

 

Supplementary info

 

 

For those looking for high spermidine foods, spermidine content in nmol/g this paper used:

 

 

Wheat germ        2440

Soybean            854

Mushrooms          651

Peas               449

Broccoli           309

Polenta            297

 

Apples             193

Cereals mixed      167

Salad              150

Whole-grain bread  129

Cheese             113 (19 sorts excl. Cheddar)

Potatoes            96

 

 

 

 

 

 

[normalizing]

very interesting table. "salad" has it quite high. tuna salad, chicken salad, salad made of turds? undeclared. very very good table.

next we have, the highest possible amount of spermidine ever in the table, "other". i must be guessing here, other as in anything else besides this table which might be absolutely anything, maybe giraffe neck, or orangutan's ass?

 

my point is, where is the damn source for good quality spermidine powder!?

Edited by hazy, 31 August 2017 - 06:00 AM.

[Harkijn]

My point is, where is the damn source for good quality spermidine powder!?

Did you notice the large amount of spermidine in wheat germs? Two tablespoons daily in your smoothie or dessert will give your spermidine intake a huge boost.

[normalizing]

wheat germ contains wheat and germ. i dont need this. hence, pure spermidine powder is the best way to go

[Advocatus Diaboli]

hazy, Dr. Perlmutter might just agree with you.

One of his books:

 

"Grain Brain: The Surprising Truth about Wheat, Carbs, and Sugar--Your Brain's Silent Killers"

[mikey]

hazy, Dr. Perlmutter might just agree with you.

One of his books:

 

"Grain Brain: The Surprising Truth about Wheat, Carbs, and Sugar--Your Brain's Silent Killers"

 

Good thought!

 

We can take/use all the best age-reversal tools, but one fundamental is that we age LESS if what we consume does not AGE us.

 

Wheat and sugar AGE us.

 

There's so much data it boggles the mind that scientists that study aging eat wheat AND/or sugar.

 

I was at an anti-aging meeting and one anti-aging doctor brought some kind of sugary cake to share.

 

He also had a little basket ball stomach, indicating visceral fat and insulin resistance.

[mikey]

very interesting table. "salad" has it quite high. tuna salad, chicken salad, salad made of turds? undeclared. very very good table.

next we have, the highest possible amount of spermidine ever in the table, "other". i must be guessing here, other as in anything else besides this table which might be absolutely anything, maybe giraffe neck, or orangutan's ass?

 

my point is, where is the damn source for good quality spermidine powder!?

 

I've only used  pure spermidine.

 

https://www.scbt.com...midine-124-20-9

 

If you want to gross your friends out make the spermidine and then hold it up to your friends's nose.

 

Smells just like cum, because it IS the essence of sperm.

[normalizing]

thanks buddy! first time i see an actual supplier of spermidine. now, did you personally order from them and it worked fine without you being affiliated with any company as much of those sites ask? i mean, no real legal problems ordering as general consumer, right? ive had problems before where they ask for license and company and address and such, but just before i bother tomorrow , i wish to ask if its worth the time, thanks

[mikey]

thanks buddy! first time i see an actual supplier of spermidine. now, did you personally order from them and it worked fine without you being affiliated with any company as much of those sites ask? i mean, no real legal problems ordering as general consumer, right? ive had problems before where they ask for license and company and address and such, but just before i bother tomorrow , i wish to ask if its worth the time, thanks

 

Actually, I just Googled that site. They do not require that you be a business, though. But their price in EU is higher than the site that I bought it from, as below.

 

I have ordered it from https://phytotechlab...permidine.html and they didn't require a business either, but they say on the page that they might ask what you intend to use it for. I don't recall that they asked me about use, but I would have just said "For research." They also shipped it to my home address, where for some other molecules I have had to use my business address because they would tell me that they can't ship to a residence, even when I say that I run a business from home and have a small lab.

 

I just pulled the bottle that I have out of the fridge and looked at the label, so that I could be sure of what I am reporting.

 

Note, the first time I bought it it was dry waxy/powder and smelled exactly as expected, like cum.

 

The second time I ordered from them it arrived as a liquid - it must have somehow melted in transit - but smelled like it should smell so I called them and complained about it being liquid and they sent me the clean dry product, which I mixed and am still using occasionally. I retained the liquid, which is kept near freezing.

 

It smells like it's real. I don't know why it would come as a liquid, except that they acknowledged that it wasn't alright and sent me the dry (fresh) version. So it seems that they are honorable.

 

I expect that the liquid will work just fine.

 

However, if someone that knows chemistry would tell me that it is likely just somehow hydrated because it is hygroscopic, but likely still OK I will use it when I run through what I have mixed.

 

Actually, it smells a bit like it might be rancid. I've kept it at about 35 degrees for many months. Maybe it is somewhat spoiled.

 

Enjoy!

Edited by mikey, 03 September 2017 - 03:41 AM.

[mikey]

 

hazy, Dr. Perlmutter might just agree with you.

One of his books:

 

"Grain Brain: The Surprising Truth about Wheat, Carbs, and Sugar--Your Brain's Silent Killers"

 

Good thought!

 

We can take/use all the best age-reversal tools, but one fundamental is that we age LESS if what we consume does not AGE us.

 

Wheat and sugar AGE us.

 

There's so much data it boggles the mind that scientists that study aging eat wheat AND/or sugar.

 

I was at an anti-aging meeting and one anti-aging doctor brought some kind of sugary cake to share.

 

He also had a little basket ball stomach, indicating visceral fat and insulin resistance.

 

 

I see that some people don't like what I said, but if you want Advanced Glycation Endproducts (AGE's), eat sugar and/or wheat.

 

One way to enrage a drug addict is to tell them that they are addicted, so I put my foot in it, saying that sugar and wheat AGE us because there are so many sugar and wheat addicts, even when logic says to avoid them if you want to slow or reverse ageing. 

 

Wheat contributes complex carbohydrates (sugars) at a tremendous rate and browning it increases AGE's even more.

 

As to references to read:

 

See the before and after photos of the woman. I have similar photos where I looked 20 years older than I do now back in 2007, when I went through a period of being careless with my food consumption, eating whatever pleasured me.
http://www.wheatbell...-aging-process/

"This is yet another example of an adverse effect of grain consumption that has nothing to do with “gluten,” as these youth-preserving effects are due to elimination of the amylopectin A carbohydrate of wheat and grains. Gram for gram, ounce for ounce, the amylopectin A starch of grains raises blood sugar higher than any other carbohydrate or sugar, even table sugar."

 

https://www.ncbi.nlm...les/PMC3704564/

 

http://thepaleodiet....n-end-products/

 

I apologize if I am not more thorough in rendering citations, but I've spent dozens (hundreds?) of hours studying this over the last 40+ years and my friends can confirm the age-reversal that has takes place when I avoid these "foods." And when I've gone back to eating them I age faster and then reverse it when I return to avoiding them. To me it is consistent with my own experience.

 

I suggest that people experiment with a more "paleo" type diet.

 

Best intentions, but fire away if this pissed you off!

[mikey]

wheat germ contains wheat and germ. i dont need this. hence, pure spermidine powder is the best way to go

 

However, a small amount of wheat germ to glean the spermidine isn't going to cause a lot of AGEing.

[aribadabar]

 

wheat germ contains wheat and germ. i dont need this. hence, pure spermidine powder is the best way to go

 

However, a small amount of wheat germ to glean the spermidine isn't going to cause a lot of AGEing.

 

 What is the daily  spermidine dosage you are aiming for?

 

Thanks!