179 replies to this topic

[Flex]

@ savagek

 

just dump trouble shooting for what it´s worth:

 

Could it be Heavy-metals or any other poisioning ? Testing is afaik below 100 Dollars for ~3 Elements and it could explain maybe the apparently normal MRI result but also the gradual decline. Unless theres no actuall shrinkage of Brain-areas evident or something.

 

 

 

 

 

[Kinesis]

Without contradicting psychejunkie's points, can you give a quick update? I am contemplating going on that regimen today so would appreciate reading about your experience so far. The one reason that it it I am hesitant I'd that, at first sight, this one does seem like an incredibly unhealthy diet actually....

 

Yeah it sounds pretty unhealthy to me too ... but that would also depend on what time frame you were talking about.  I wouldn't view it as a permanent lifestyle, but as a therapy it could be just the ticket.  You could try it for a few weeks, then start adding some greens, berries, and gradually morph into a longer term healthier diet.  I've had good results before from doing this with similar keto-style diets.

[savagek]

@ savagek

 

just dump trouble shooting for what it´s worth:

 

Could it be Heavy-metals or any other poisioning ? Testing is afaik below 100 Dollars for ~3 Elements and it could explain maybe the apparently normal MRI result but also the gradual decline. Unless theres no actuall shrinkage of Brain-areas evident or something.

 

 

This is interesting. Will definitely look into it 

[IP3]

Normalizing: you can cure abuse of cocaine overnight, just search baclofen. However there can be serious problems after even one dose of psychostimulants.
I had never seen cocke, got my impairment after methylphenidate. And the problem was debilitating. So please dont speak about ball examination.

Diet update: i fell completly normal now. But i have found two substances that may be responsible for my total (98% recovery to normal mind activity). So someobe else should try this diet to confirm. ADD is still a problem. But not as big as brain fog/brain tension.

[Flex]

 

@ savagek

 

just dump trouble shooting for what it´s worth:

 

Could it be Heavy-metals or any other poisioning ? Testing is afaik below 100 Dollars for ~3 Elements and it could explain maybe the apparently normal MRI result but also the gradual decline. Unless theres no actuall shrinkage of Brain-areas evident or something.

 

 

This is interesting. Will definitely look into it 

 

 

The initial though was that Heavy metals can induce vasoconstriction (among others like muscle cramps) via.. dont know.. ion channel (e.g. Calcium, Potassium, Sodium, Chloride) modulation ?

So let say,if they are able to modulate on a lagre scale ion channels, then they could affect other ion channel functions as well e.g. memory, attention & etc.

 

Vascular effects of ambient pollutant particles and metals.

http://www.ncbi.nlm....pubmed/16842137

 

Low Mercury Concentration Produces Vasoconstriction, Decreases Nitric Oxide Bioavailability and Increases Oxidative Stress in Rat Conductance Artery

http://www.ncbi.nlm....les/PMC3492199/

[SwissGuy]

Normalizing: you can cure abuse of cocaine overnight, just search baclofen. However there can be serious problems after even one dose of psychostimulants.
I had never seen cocke, got my impairment after methylphenidate. And the problem was debilitating. So please dont speak about ball examination.

Diet update: i fell completly normal now. But i have found two substances that may be responsible for my total (98% recovery to normal mind activity). So someobe else should try this diet to confirm. ADD is still a problem. But not as big as brain fog/brain tension.

 

It is great news that you are feeling back to normal now. Can you give us more details about what you think led to improvement?

 

Was it the diet? How long were you on it, and did you do exclusively eggs + meat? How did it go? When did you start noticing an improvement?

 

Were any other factors involved such as any of the meds/'substances' you mentioned previously?

 

How are you doing now? Did you stop the diet once you felt better?

 

Thank you for these infos - those will be much appreciated.

[MetaphasicSystems]

I stopped the diet for the most part about four weeks after recovery.
Glad it worked for you.

Wish assholes would think outside the box on this forum and answer my questions and help me out


Truly Blessed.

[YOLF]

 

 

That substance is called cocaethylene, which is produced by the liver in the presence of cocaine and alcohol. Cocaethylene is a metabolite which is much more toxic than cocaine alone (Julien et al., 2011). As indicated above, this combination can result in death much more quickly than in the presence of cocaine alone.

 

I've seen cocaethylene referred to as "supercoke," and it's pretty bad news...

 

In addition to that, a side effect of cocaine and alcohol is stroke and alcohol and xanax can lower respiration, which in combination with cocain would lead to asphyxiation and/or brain damage from lack of oxygen under increased demand... stop taking advice from your drug dealer is my suggestion... they're trying to kill you or sell you more shit. Maybe trying to get you dependent on meth or something to compensate for the brain damage they've caused.

 

You need to treat yourself for stroke and asphyxiation... and potentially some form of liver damage which won't show up on routine blood tests. Most doctors have never thought about saving a patient from drug abuse pathologies and users and take the stance that you've done it to yourself and deserve it... which is quite inhumane in my opinion but appears to be the truth?

 

Here's my guess as to what might help you, but I'd contact a professional... I'm guessing LEF could do you some good, but I've not seen a rehab center that will do anything but help you cope with the brain damage and I'm just hoping LEF can do something for you.

 

Anyways... I'm thinking

Grapeseed extract or pine bark extract (increased blood flow)

Rutin? iirc it helps improves management of vasodilation/constriction in finer vessels.... maybe it was purslane? 

Pregnenolone (good for strokes)

Progesterone?

Alpha GPC

Taurine (a few grams) for liver health

Milk thistle for liver health

Vitamin C AND Ester C

Perhaps tocotrienols (with low or no tocopherols), and if you take this it should be safe to use IGF1 as well

Blueberry Extracts (good for general brain health)

Quercetin (senolytic to help replace damaged brain cells?)

Lion's Mane?

Bacopa?

 

 

Imagine there might be more and better for what you're going through... so I'd definitely be looking for a drug abuse recovery specialist or hoping LEF can help. 

[YOLF]

i cant believe this thread has been taken so serious up to 6 pages about some idiot teenager snorting coke first time and having problems. first time i did coke i had severe depression and anxiety next day which was a joke compared to the coke abuse that followed years thereafter, this guy needs to have his balls checked first before he posts here again

Try to be kind, it seems he might genuinely be having some problems. See my post.

[psychejunkie]

 

 

 

That substance is called cocaethylene, which is produced by the liver in the presence of cocaine and alcohol. Cocaethylene is a metabolite which is much more toxic than cocaine alone (Julien et al., 2011). As indicated above, this combination can result in death much more quickly than in the presence of cocaine alone.

 

I've seen cocaethylene referred to as "supercoke," and it's pretty bad news...

 

In addition to that, a side effect of cocaine and alcohol is stroke and alcohol and xanax can lower respiration, which in combination with cocain would lead to asphyxiation and/or brain damage from lack of oxygen under increased demand... stop taking advice from your drug dealer is my suggestion... they're trying to kill you or sell you more shit. Maybe trying to get you dependent on meth or something to compensate for the brain damage they've caused.

 

You need to treat yourself for stroke and asphyxiation... and potentially some form of liver damage which won't show up on routine blood tests. Most doctors have never thought about saving a patient from drug abuse pathologies and users and take the stance that you've done it to yourself and deserve it... which is quite inhumane in my opinion but appears to be the truth?

 

Here's my guess as to what might help you, but I'd contact a professional... I'm guessing LEF could do you some good, but I've not seen a rehab center that will do anything but help you cope with the brain damage and I'm just hoping LEF can do something for you.

 

Anyways... I'm thinking

Grapeseed extract or pine bark extract (increased blood flow)

Rutin? iirc it helps improves management of vasodilation/constriction in finer vessels.... maybe it was purslane? 

Pregnenolone (good for strokes)

Progesterone?

Alpha GPC

Taurine (a few grams) for liver health

Milk thistle for liver health

Vitamin C AND Ester C

Perhaps tocotrienols (with low or no tocopherols), and if you take this it should be safe to use IGF1 as well

Blueberry Extracts (good for general brain health)

Quercetin (senolytic to help replace damaged brain cells?)

Lion's Mane?

Bacopa?

 

 

Imagine there might be more and better for what you're going through... so I'd definitely be looking for a drug abuse recovery specialist or hoping LEF can help. 

 

 

Stroke, Tissue injury or asphyxiation would have been shown on MRI/CT scans; But Op, IP3 and SwissGuy did mention no indication of abnormality or disorder on any tests including Blood Test, MRI/CT Scan nor EEG!

[YOLF]

 

 

 

 

That substance is called cocaethylene, which is produced by the liver in the presence of cocaine and alcohol. Cocaethylene is a metabolite which is much more toxic than cocaine alone (Julien et al., 2011). As indicated above, this combination can result in death much more quickly than in the presence of cocaine alone.

 

I've seen cocaethylene referred to as "supercoke," and it's pretty bad news...

 

In addition to that, a side effect of cocaine and alcohol is stroke and alcohol and xanax can lower respiration, which in combination with cocain would lead to asphyxiation and/or brain damage from lack of oxygen under increased demand... stop taking advice from your drug dealer is my suggestion... they're trying to kill you or sell you more shit. Maybe trying to get you dependent on meth or something to compensate for the brain damage they've caused.

 

You need to treat yourself for stroke and asphyxiation... and potentially some form of liver damage which won't show up on routine blood tests. Most doctors have never thought about saving a patient from drug abuse pathologies and users and take the stance that you've done it to yourself and deserve it... which is quite inhumane in my opinion but appears to be the truth?

 

Here's my guess as to what might help you, but I'd contact a professional... I'm guessing LEF could do you some good, but I've not seen a rehab center that will do anything but help you cope with the brain damage and I'm just hoping LEF can do something for you.

 

Anyways... I'm thinking

Grapeseed extract or pine bark extract (increased blood flow)

Rutin? iirc it helps improves management of vasodilation/constriction in finer vessels.... maybe it was purslane? 

Pregnenolone (good for strokes)

Progesterone?

Alpha GPC

Taurine (a few grams) for liver health

Milk thistle for liver health

Vitamin C AND Ester C

Perhaps tocotrienols (with low or no tocopherols), and if you take this it should be safe to use IGF1 as well

Blueberry Extracts (good for general brain health)

Quercetin (senolytic to help replace damaged brain cells?)

Lion's Mane?

Bacopa?

 

 

Imagine there might be more and better for what you're going through... so I'd definitely be looking for a drug abuse recovery specialist or hoping LEF can help. 

 

 

Stroke, Tissue injury or asphyxiation would have been shown on MRI/CT scans; But Op, IP3 and SwissGuy did mention no indication of abnormality or disorder on any tests including Blood Test, MRI/CT Scan nor EEG!

 

 

To what extent do these scans work? Would the hallmarkings of single acute overdose be similar to what is looked for with long term abuse? The unique combination may lead to less detectable damage. It's not necessarily asphyxiation, it could be the result of several hours of oxygen deprivation or a combination of minor changes that might only show significance in combination. I could go on on the possibilities... I doubt baclofen is a solution to his problem as a one time user.

[IP3]

I was on the diet for about one week, but breakthrough was sublingual astragalus extract. Once diet help me i stoped it because of horrible constipation and light liver pain.

 

I took 0,5 ml c60 in olive oil for my liver.... aaand all positive effects were gone.. for four days . Tension, brain fog, and felling "like there is something wrong with my brain vessels"  come back. Some time ago i post a question in topic "c60 side effects" if anyone who have side effects from c60 have history of previous (ab)using of addictive drugs.

 

[maik2013]

The "cocaine" in europe is max 25%. Then you have good stuff. I have read experiences from people, who have said that pure cocaine is much more subtle. I also know that in Mexico they put something in the cocaine, which is used for animals usually. I'm quite sure that cocaine use, has caused multiple allergies to me. This has caused me to live ultra healthy. I don't know how old you are, but if you're below thirty,you should exercise A LOT. I have visions problems every winter. It's a horrible feeling, if you suddenly see everything blurred. But it's a sensitivity/allergy issue with me. People with migraines suffer A LOT. What i'm trying to say is, that you should stop focussing on brain damage. The average drug user takes WAY more than that, often for years and in all kind of different combinations. 

[Flex]

 

 

 

Stroke, Tissue injury or asphyxiation would have been shown on MRI/CT scans; But Op, IP3 and SwissGuy did mention no indication of abnormality or disorder on any tests including Blood Test, MRI/CT Scan nor EEG!

 

 

To what extent do these scans work? Would the hallmarkings of single acute overdose be similar to what is looked for with long term abuse? The unique combination may lead to less detectable damage. It's not necessarily asphyxiation, it could be the result of several hours of oxygen deprivation or a combination of minor changes that might only show significance in combination. I could go on on the possibilities... I doubt baclofen is a solution to his problem as a one time user.

 

 

I heard that a functional MRI can show some dysfunctional parts.

afaik, a normal MRI cant show whether there are functional cells nor whether any microvessels are destroyed.

 

My source are the effects of cocaine and micro-strokes which dont show up by the resolution of a normal MRI.

However I guess a professionals opinion is neede to estiamte whether there could be an impact in this case. 

 

Edited by Flex, 18 June 2016 - 11:18 PM.

[savagek]

 

 

 

That substance is called cocaethylene, which is produced by the liver in the presence of cocaine and alcohol. Cocaethylene is a metabolite which is much more toxic than cocaine alone (Julien et al., 2011). As indicated above, this combination can result in death much more quickly than in the presence of cocaine alone.

 

I've seen cocaethylene referred to as "supercoke," and it's pretty bad news...

 

In addition to that, a side effect of cocaine and alcohol is stroke and alcohol and xanax can lower respiration, which in combination with cocain would lead to asphyxiation and/or brain damage from lack of oxygen under increased demand... stop taking advice from your drug dealer is my suggestion... they're trying to kill you or sell you more shit. Maybe trying to get you dependent on meth or something to compensate for the brain damage they've caused.

 

You need to treat yourself for stroke and asphyxiation... and potentially some form of liver damage which won't show up on routine blood tests. Most doctors have never thought about saving a patient from drug abuse pathologies and users and take the stance that you've done it to yourself and deserve it... which is quite inhumane in my opinion but appears to be the truth?

 

Here's my guess as to what might help you, but I'd contact a professional... I'm guessing LEF could do you some good, but I've not seen a rehab center that will do anything but help you cope with the brain damage and I'm just hoping LEF can do something for you.

 

Anyways... I'm thinking

Grapeseed extract or pine bark extract (increased blood flow)

Rutin? iirc it helps improves management of vasodilation/constriction in finer vessels.... maybe it was purslane? 

Pregnenolone (good for strokes)

Progesterone?

Alpha GPC

Taurine (a few grams) for liver health

Milk thistle for liver health

Vitamin C AND Ester C

Perhaps tocotrienols (with low or no tocopherols), and if you take this it should be safe to use IGF1 as well

Blueberry Extracts (good for general brain health)

Quercetin (senolytic to help replace damaged brain cells?)

Lion's Mane?

Bacopa?

 

 

Imagine there might be more and better for what you're going through... so I'd definitely be looking for a drug abuse recovery specialist or hoping LEF can help. 

 

 

Thanks for the info. Not too sure what LEF is. Tried googling it but couldnt come up with anything.

[YOLF]

LEF = Life Extension Foundation

[Flex]

Excuses I ´ve forgot to tell that its possible to test for all or at least nearly all heavy-metals i.e. to get a bargain. The price is arround 200 Euro in Germany.

Make sure to find a reliable lab (mayo clinic?) which offers testing for the most elements, since there are also black sheeps arround

and it could not be sufficient to look only for the few usual heavy-metals instead of e.g. Arsenic or Iridium & etc as well.

 

Edited by Flex, 23 June 2016 - 10:37 AM.

[IP3]

I must tell you that after all this intterventions in stressful situations i cannot think properly. I am way too slow.

Almost all tension has gone, but my analytical skills are hampered as my ability to convert my ideas to words. And i used to be orator!

Also reading books is not pleasurable like it used to be.

Things that most helped me was indirect dopamine agonists, but their actions was short-acting.  (tianeptine +baclofen- the best, but only for one day..., i thought that baclofen will prevent tianeptine tolerance,)

 

Did you know any d1 dopamine antagonists? I used small doses of sulpiride and trimetazidine to re-sensitize my dopamine receptors. However those drugs act only on d2 receprors, and d1 are involved in problem-solving skills.

Edited by IP3, 24 June 2016 - 06:44 PM.

[YOLF]

Testosterone supps or just working out always make me smarter. Gets you all the right dopamine receptors in all the right places!

Definitely works best when getting high output workouts though. None of that walk around the block stuff...

[IP3]

Anyone of you tried tricyclics for this type of imparment? I think that someone wrote here something about it.

[IP3]

Ok, now i can say that i have found the cure. I fell 100% normal now. The cure was nitrendypine. (but i also take baclofen and tianeptine) Nitrendypine is calcium channel blocker used to treat hypertension. Currently i am taking it from one week. I notice huge improvement after 2nd day (5mg morning, 5mg evening)

 

As i mentioned in my posts before my problem started when i used mph without my "neuroprotective sack" and got hypertensive crisis. One of drugs in this stack was nitrendypine. (http://www.ncbi.nlm..../pubmed/1941571 it is both cardio and neuroprotective)

 

My mental clarity, verbal fluency and mathematical skills come back. Music again can induce euphoria. Savagek, try nitrendypine!

[YOLF]

Congrats! Thanks for letting us know what worked. I'm not familiar with this one, what does it suggest happened?

[IP3]

Well i dont know what happened.And i wouldn't Iike to guess. I know that ccblockers protects against excitoxicity, and inhibit neurotransmiters relase. Also they are widening brain blood vessels and many of them are used as mood stabilizers.

[Blackkzeus]

What made you try nitrendypine?

[IP3]

I used it previously with methylphenidate to slow tolerance building and as a cardio-neuroprotective drug. I thought that my impairment can be vascular orgin. So i tried to dilate blood vessels.. just intuition. 

[IP3]

Ofcourse nitrendypine may just reverse tolerance to tianeptine (opioid, dopaminergic). I will report news in few days.

[SwissGuy]

IP3, That's great news - congratulations. I have now been  in nutritional ketosis for 2.5 weeks and while it helps, and definitely has positive effects on cognition, I do, by no means, feel 'cured' yet.

 

The thinking around cerebral vasodilation is interesting, especially because stimulant abuse might disrupt the natural systems of dilation and constriction in brain vessels? I have been taking a bit of gingko bilboa, which seems to be a vasodilator, and it has been helping. So I wonder: is there anything more effective than gingko in that regard? Any potent cerebral vasodilators? I guess I'd need a prescription for things like nitrendypine.

 

How did you manage to get it prescribed? What would I have to tell the Dr? Any risks?

 

Are there any natural alternatives? How about grape seed extract or so?

[IP3]

Swiss, i have few physicans in family so there were no problem. Nitrendypine act on me as very good mood stabilizer. I also tried nicergoline but effect wasnt even half as good. So, perhaps it is not just vasodilatation.

[IP3]

Extremely important update.

 

After initial success with baclofen tianeptine and nitrendypine my problem arised again.

I felt something like lego brick in my forhead, brain fog, somnolence, and dull pain below my right eye. Also depression kick again. 

 

It was just coaccident that at periodic medical testing my ophtalmologist tested my intraoccular pressure.

Left eye 25 right 30

 

I was prescribed bimatoprost eyedrops. It was huge relief. My tension diaperad in almost magical way.

 

Did you also tested your eye pressure?

[IP3]

Update: I am fine, i never felt better. I am currently taking tianeptine, baclofen, rhodiola, and bromantane (i thing i would never again take methylphenidate for adhd, bromantane and tianeptine are enough good).

 

Of course lumigan every 24 hours is absolute must. If i dont take it at time pressure build ups fairly quickly. I consider iridotomy.

 

Topic is dead so i assume that you checked my theory and everything is fine?