6 replies to this topic

[YOLF]

I've got two brands of the same molecule in front of me. One is pure white and the other is a slightly off white. 

 

The pure white powder is tasteless and sampling it with my tongue doesn't present any effects.

 

The off white (a little beige) one leaves a taste on my tongue (I'm at a loss to describe it, maybe of ammonia?) and leaves the spot on my tongue where I sampled it a little numb.

[niner]

What's HMB?

[YOLF]

HMB

 

 

[niner]

Hydroxy Methylbutyrate.  OK.  It sounds like the smelly one is a bad batch, at least in that it's not as pure as the other stuff.  Whether or not it's actually harmful is an open question, but it doesn't sound good.  As an aside, it's kind of an anti-longevity compound.  It activates MTOR and suppresses autophagy, or at least those are considered plausible mechanisms for it.  Either would be bad for longevity.  Use with care.

[YOLF]

I'm open to changing my mind, but as I had read it, it prevented catabolism in muscles as would thus prevent muscles from becoming damaged by strenuous activity. Part of anti-aging I figure should be preventing damage while another is to remove cells that have become damaged. My strategy is to ramp up my immune system and prevent damage that might become aging.

 

What do you think about testing it with a public labs spectrometer?

[niner]

The prevention of catabolism is probably related to (if not identical to) the suppression of autophagy.  The problem is that one of the key things in anti-aging is getting rid of damaged cells and molecules, which requires functional autophagy.   I don't think that muscle catabolism is going to be a significant problem with any real world workout that you're likely to do, unless you are doing one of those crazy person 150 mile runs, or something truly abusive like that.  If you suppress autophagy, then you aren't stopping the damage, you're just stopping the cleaning up of the damage.  That leaves you in a worse state at the end.

 

The public labs spectrometer is a pretty cool device, but I think you'd probably want to run it through an HPLC so you can separate the sample into discreet substances and see the extent of contamination.

[YOLF]

They do have some stuff similar to an HPLC. The option they show in pics/vids is to have a stationary light below a glass dish with the spectrometer above. How much different is prograde HPLC?