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Q about study showing deprenyl and shortened life


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#31 power.bulls.x

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Posted 06 January 2006 - 04:08 AM

No this part:

[A personal note: After all this, sometimes confusing, information about deprenyl, you are probably wondering how much, if any, deprenyl I take. In 1989, I began taking 15 mg. a week. I soon reduced the dosage to 5 to 10 mg. of deprenyl weekly. In 1996, I reduced my dose to 5 mg. a week and started using liquid deprenyl citrate. I also take 1000 mg. of NAC per day and at least 800 I.U. of vitamin E and 3200 mg. of vitamin C per day.]


Well that doctor is also in his like +60s, so it's not really imformative regarding the high-dose study his buddy conducted. Though I found this really interesting: The half-life of MAO-B inhibition in humans has been measured to be about 40 days, therefore, deprenyl probably need not be taken daily by persons who do not have a neurological disease.

Also, what do you all think about this. I tried 1/2 a tab of deprenyl today and it I felt pretty good for about 4hrs, but then I started to get really sleepy. I ended up taking a huge nap from like 4pm-10pm. In the past, I tried reboxetine which blocks dopamine reuptake in the front part of the brain in hopes that the norepherenine (I spelled that wrong) will soak longer and not reuptake through the dopamine receptors. That said, reboxetine also really make me feel sleepy and lethargic.

Does anyone have some info regarding what might be going on?

reboxetine makes feels so determined and .
i can sit down i get boring stuff done . it makes so determined .
But i t also reduced my sleep time to 5 hours.
i am just wondering how to safly use that stuff :
i have deprenyl,provigil,galantamine on hand.
i am scared to use deprenyl and provigil while i am on reboxetine.
i ve heared that it reduce choline and the whole cholinergic system . is that true ?

#32 ozone

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Posted 16 January 2006 - 07:54 PM

@PBX06

Well, I tried reboxetine but it didn't seem to have any positive effect for me; I just got tired. Now, that stuff is the EXACT same as Strattera which has positive effects on me. They are both made by different companies, but are the identical drug. But if it's working for you, I say stay on it. :) As for deprenyl,provigil,galantamine... well, if you're taking reboxetine and it works for you, maybe you have low noradrenaline levels like me. If so, I found deprenyl absolutely HORRID. Have you tried it before? I caution you if you have not. When I took it, I felt so tired for about 8 days. Just 1 fricking drop man (or 1/2 a tab). Other folks say it gives them tons of energy, but holy crap, not me. I physically could not move out of bed, I just lay there. Even when I was thirsty I couldn't get up because I was just too tired. So if you take it, try a single drop and see how it affects you.

As for galantamine, I've taken it and well, it's not going to be as noticable an effect as other drugs, but it works well w/o any noticable side effects for me.

Finally, I have no info on provigil.

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#33 Guest_da_sense_*

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Posted 17 January 2006 - 09:53 AM

pbx06
i wouldn't use reboxetine and deprenyl at same time, better be safe than sorry.

what happened to ozone is very rare, i never heard of such incidents in any of my readings about deprenyl. i still doubt it could have been caused by something else (bad products, allergy to something else in product etc)...

#34 kerastasey

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Posted 21 January 2006 - 01:08 AM

Isn't the problem with Down's syndrome people that they produce far too much SOD?

And how much does 1mg Deprenyl really help increase SOD by? More than say 500mg GliSODin?

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#35 mewild

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Posted 03 October 2006 - 12:01 PM

By the time everyone in their 20's are 60+ who knows what science will come up with to fix brain problems. Thus I dont feel that small amounts of Deprenyl are dangerous to life...




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