37 replies to this topic

[Anthony_Loera]

 

Can you please tell me which type of product is metacurcumin from below, as is clear all these types are focused on different problems.

 

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Please read the first page of this thread.

MetaCurcumin is compared to all of those you previously posted... and pretty much beat them all in absorption, bioavailability and how long the curcumin stayed in a subject.

 

Curcumin molecule:

The curcumin molecule is the same across all products you mentioned, and providing the "right dose" likely exerts all the effects and benefits you just mentioned. It is the formulation that may have an impact on bioavailability, since it allows curcumin to work in your body longer, and help provide the benefits. 

 

That is why MetaCurcumin is focused on a high bioavailability.

We guarantee MetaCurcumin is better than those you mentioned in bioavailability, or your money back.

 

I hope this helps,

A

[KieranA001]

Is this anything to worry about? Source is https://selfhacked.c...ith-references/

 

At low doses (as shown in many studies above) it acts as a potent antioxidant, scavenging ROS.  At high doses it is suggested that it may actually induce ROS, leading to DNA damage ®

 

 

[Anthony_Loera]

We have not seen evidence of ROS in human studies, only positive studies since that 2010 study.

 

Thanks

A

[Forever21]

What should a healthy person expect from taking this? Extra energy? Better skintone? Or hardly anything visible (must look under the surface with medical test to measure benefits?)

[Pantheon]

The Clinical study posted on this thread to support the bioavailability of MetaCurcumin was designed to assess the bioavailability of the NovaSOL® Curcumin, a proprietary micellar curcumin formulation manufactured by AquaNova AG based in Germany, compared to the bioavailability of native and micronized powder.  The full study is posted at:

http://onlinelibrary....201300724/full

 

In this study participants were administered 500mg curcuminoids, containing 410mg curcumin, 80 mg DMC and 10mg BDMC as native powder, micronized powder and liquid micelles. Curcumin micelles were composed by 7% curcumin powder (equivalent to 6% curcumin) and 93% Tween-80.
 

1) Does the MetaCurcumin formulation include the NovaSOL® Curcumin manufactured by AquaNova? Is this the same formulation as the one used in the clinical study, if not how the MetaCurcumin formulation differs from the NovaSOL® used in the study? 

 

2) How about the “Supplement Facts” of the MetaCurcumin formulation? Which other additives are included in this product?  It would be really helpful for us to compare the different product formulations and strengths currently available in the market and also be aware of possible additives and allergens included. Unfortunately the Supplement Facts of the MetaCurcumin formulation don’t appear to be published online, neither on this thread nor at the manufacturer’s page.

 

3) How about the side effects of the curcumin micelles that were reported by participants in this study?

According to this study approximately 54% of women experienced mild nausea (7 out of 13 women). It could be because of the micellar curcumin staying in the bloodstream for too long or because of others reasons that worth further investigation. A total 12 adverse reactions were reported. However those side effects were not reported when participants took the other 2 formulations.

 

4) Besides the bioavailability on healthy subjects, are there any published clinical human studies to support the biological activities and therapeutic efficacy of the curcumin micelles in certain conditions like arthritis, inflammation and cognition?

 

To date no clinical human studies of curcumin micelles are published so far in order to draw conclusions of their therapeutic efficacy on certain clinical conditions, contrary to other popular formulations like Meriva,  BCM-95, Theracurmin  and Longvida Curcumin which come with multiple clinical trials and some supportive evidence to back up their efficacy.

 

5) How much micellar curcumin is absorbed by the body tissues where it can show potential biological effectiveness?

Beyond pharmacokinetics like AUC and blood concentration there are multiple factors than can determine the efficacy of  certain compounds. The NovaSOL® study includes the following statement “over 98.8% of the ingested curcumin was either excreted via the bile and feces or may have been distributed by body tissues, where it may potentially exert biological activities”. 

 

Edited by Pantheon, 07 July 2017 - 11:25 PM.

[Malf]

 

 

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MetaCurcumin (micellar crucumin) has

up to 277 times Bioavailability of standard curcumin. 

 

Winner? Metacurcumin

 

 

Just for the sake of completeness. According to the following study, micellar curcumin has 277 times the bioavailability as standard curcumin in women only, and 144 times the bioavailability of standard curcumin in men. There was no explanation on why there was a difference between the sexes.

 

http://www.ncbi.nlm....pubmed/24402825
 

 

 

yeah that is baffling, why would it be more absorbably for women than men? it doesn't explain why

 

I currently take Solgar Full Spectrum Novasol Curcumin, where does metacurmin get their Curcumin is it Novasol from Aquanova as in the study? or is it a different one?

Edited by Malf, 30 November 2017 - 06:11 AM.

[yxmees]

Are there any working discount codes for revgenetics? Also shipping is ridiculously expensive, to my country more than price for 2 bottles of metacurcumin

Edited by yxmees, 24 June 2018 - 07:15 PM.

[John250]

If the capsules are $37 for 30 day supply and the pump canister is $60 for an almost 300 day supply why would anyone get the capsules? It says the capsules have extra curcuminoids are those really that beneficial?