83 replies to this topic

[Baten]

For some time now I have been suffering a sudden and serious loss of interest in all things sexual; really low libido, lack of arousal; loss of morning wood, ...

 

Some background, when I was younger I never had any of these problems, I was over-sexual if anything. I never really had any long-term relationships though, and masturbated way too much (many times a day). I'm thinking I'm probably quite desensitized: watching a pretty girl pass me by didn't really pique my interest anymore. And eventually, even porn didn't really interest me that much, it became more of a habit than anything.

 

I'm now in my mid-twenties and stopped watching porn, and to be honest that's when the "problems" really started. I suffered from erection problems and complete lack of libido. I figured I could either pick up my old habits again and see if I'd recover, or keep "abstaining" and see if things would get better in time. (Reading on this subject, I find several cases of people in their twenties, their situation similar to mine...).

 

That was 3 months ago, and while things are better the situation is still far from "solved". I keep thinking I really shouldn't have this much trouble at my age. I know, things should get better in time, but problem is I'm currently in a more serious relationship with a girl, and while she's very understanding I really want my "old self" back. I need things to get better.

 

What I tried so far

 

- Herbs: Tongkat ali, horny goat weed, maca, tribulus

Effects were subtle and mostly inconsistent. No real improvements.

 

- Sports: I exercise a lot. I've tried supplementing with lots of L-arginine for 'blood flow', too.

Don't really notice any direct improvements, but exercising sure can't hurt.

 

- Drugs: I have Lilly pharm. Tadalafil/Cialis tablets. So fucking expensive though.

At the beginning it didn't do much, but over time these help me to actually perform when I otherwise couldn't.

I take a 5mg pill which then seems to stay around 36 hours in my blood. The effect isn't great, but it's there and it helps.

 

- Supplements: using up vitamins minerals and other herbal compounds I still have at home since why not.

Keeping my zinc levels up could be useful. So far feeling good, healthy, but no real other changes.

Currently trying;

- Adjusting dopamine levels My dopamine reward/arousal system is probably not functioning as it should.

Supplementing with Sulbutiamine and phenylpiracetam. Feeling great, studying well, but not sure beyond that.

Currently also trying out mucuna pruriens(6% l-dopa) with no real effects. Selegiline on order.

 

- Lowering cortisol & prolactin

Currently taking lots of Phosphatidyl Choline before going to sleep, no effect so far. Cabergoline on order.

 

 

Any suggestions, advice, tips and help are really appreciated. Thank you.

Edited by Baten, 25 April 2015 - 10:36 AM.

[Flex]

Low dose of Amisulpride (50-70mg) caused to me a beton dick + arrousal for 2-3 hours.

But only for the first time..

Therefore Its not suitable for Your case, I´ve mentioned it rather as an anectode.

at 100mg is afaik the mark of postsynaptic receptor inhibition which leads to a decreasae of sexuallity for a few weeks via its antipsychotic effect.

 

Afaik Males do respond on dopamine whereas Females respond rather on Serotonine, so I would look into dopaminergic and/or Testosterone

 

- Personally I´ve found Yohimbine useless and maca, catuaba, muria puama, Butea superba & etc rather weak, unless its mixed with weed.

 

- Zinc could be woth a try but dont exeed 30mg

 

- You could try hordenine or any other mao-b inhibitor like Neuravena/green oat extract, though hordenine isnt actually a mao-b inhibitor but blocks afaik this site somehow.

(I dont know much about the safety of it)

 

Here are some dopaminergic compounds:

17 Random Dopaminergic Supplements

http://www.longecity...ic-supplements/

 

Psoralea corylifolia has some dopaminergic effects. Its relative safe on the short- (testo increase) but bad on the longrun e.g. testosterone decrease, + afaik toxic

 

Mucuna pruriens "could" be stackable but releasing too much dopamine can be neurotoxic and, in the case of L-dopa, cause dyskinesias after months or years (?).

Afaik the herb contains some scondary compounds which counter the effect, so I wouldnt buy a to e.g. 90% L-dopa purificated extract but rather full spectrum.

Edited by Flex, 25 April 2015 - 12:55 PM.

[Rickpoteen]

Have you already had a blood test to look at your testosterone, estradiol, prolactin levels? It'd probably help to see if you might have too much prolactin or estrogen.

[VerdeGo]

I second the blood test. Zinc worked well for me. Raw chocolate is an aphrodisiac (due to health concerns be careful). Sulbutiamine and theanine both boosted libido for me, especially sulbutiamine. There are also studies pointing to the protective effects of taurine with testosterone (if your low libido is linked to low T), and a 180% increase in testosterone was seen in animal studies. Arginine may also be useful (in theory, at least, because of NO).

 

Porn and masturbation are more detrimental to our health than previously assumed, though you'd be locked into an asylum if you were caught doing this in the 1800s. I posted a few links below in regards to taurine, but I realize you are not an aged male rat, so YMMV. Just some suggestions...

 

http://anabolicmen.c...e-testosterone/

 

http://www.ncbi.nlm....pubmed/20804629

 

Effects of taurine on male reproduction in rats of different ages.

Yang J1, Wu G, Feng Y, Lv Q, Lin S, Hu J.

Author information

 

Abstract

BACKGROUND:

It has been demonstrated that taurine is one of the most abundant free amino acids in the male reproductive system, and can be biosynthesized by male reproductive organs. But the effect of taurine on male reproduction is poorly understood.

METHODS:

Taurine and beta-alanine (taurine transport inhibitor) were offered in water to male rats of different ages. The effects of taurine on reproductive hormones, testis marker enzymes, antioxidative ability and sperm quality were investigated.

RESULTS:

The levels of T and LH were obviously increased by taurine supplementation in rats of different ages, and the level of E was also significantly elevated in baby rats. The levels of SOD, ACP, SDH and NOS were obviously increased by taurine administration in adult rats, but the levels of AKP, AST, ALT and NO were significantly decreased. The levels of SOD, ACP, LDH, SDH, NOS, NO and GSH were significantly elevated by taurine administration in aged rats, but the levels of AST and ALT were significantly decreased. The motility of spermatozoa was obviously increased by taurine supplement in adult rats. The numbers and motility of spermatozoa, the rate of live spermatozoa were significantly increased by taurine supplement in aged rats.

CONCLUSIONS:

The present study demonstrated that a taurine supplement could stimulate the secretion of LH and T, increase the levels of testicular marker enzymes, elevate testicular antioxidation and improve sperm quality. The results imply that taurine plays important roles in male reproduction especially in aged animals.

 

It's interesting (off topic here) that taurine also lowers liver enzymes AST and ALT. 

 

http://www.ncbi.nlm....pubmed/23392896

 

Taurine enhances the sexual response and mating ability in aged male rats.

Yang J1, Lin S, Feng Y, Wu G, Hu J.

Author information

 

Abstract

It has been demonstrated that taurine is abundant in male reproductive organs, and can be biosynthesized by testis, but the taurine concentration will reduce with aging. The levels of serum LH, T, NOS, and NO were found to be obviously increased by taurine supplementation in aged rats in our previous study. In addition, aging will result in a significant decline in sexual response and function, which may be attributed to the androgen deficiency. Furthermore, NO has been proposed as a crucial mediator of penile erection. That makes us hypothesize that there is potential relationship between taurine decline and erection dysfunction in aged males. So the primary aim of the present study was to investigate the effect of taurine on male sexuality in rats. Taurine was offered in water to male aged (20 months old) rats for 110 days. The effects of taurine on the sexual response, mating ability, levels of serum reproductive hormones, and penile NOS and NO levels were investigated. The results showed that taurine can significantly reduce the EL and ML; obviously increase the ERF, MF, IF, and EJF; stimulate the secretion of GnRH, LH, and T; and elevate penis NOS and NO level in aged rats. The results indicated that taurine can enhance the sexual response and mating ability in aged male rats by increasing the level of testosterone and NO, but the exact mechanism of which needs to be further investigated.

 

[nowayout]

Get a testosterone panel. Also a thyroid panel.

I have never seen anyone get a sustainable solution to this problem with herbal remedies. They really don't work all that well and are in my opinion mostly placebo. Likewise for dopaminergics. They aren't sustainable, assuming they even work in the beginning. Fixing either testosterone or thyroid issues, if you have any, are really the only approaches that really work in the long term.

Order generic tadalafil. The Cipla brand works well and costs about a twentieth of the brand Cialis. In my experience levitra (vardenafil) works quite a bit better than the other two PDE inhibitors so you might want to try it if Cialis isn't quite doing the trick.

Edited by nowayout, 25 April 2015 - 08:40 PM.

[Baten]

 

Have you already had a blood test to look at your testosterone, estradiol, prolactin levels? It'd probably help to see if you might have too much prolactin or estrogen.

 

Had my blood checked, nothing out of the ordinary.

 

Get a testosterone panel. Also a thyroid panel.

I have never seen anyone get a sustainable solution to this problem with herbal remedies. They really don't work all that well and are in my opinion mostly placebo. Likewise for dopaminergics. They aren't sustainable, assuming they even work in the beginning. Fixing either testosterone or thyroid issues, if you have any, are really the only approaches that really work in the long term.

Order generic tadalafil. The Cipla brand works well and costs about a twentieth of the brand Cialis. In my experience levitra (vardenafil) works quite a bit better than the other two PDE inhibitors so you might want to try it if Cialis isn't quite doing the trick.

 

I'll talk to my doctor. I'm really not sure about the underlying cause. Hope I can figure it out, if other approaches are not sustainable like you say.

And I'll check out generic tadalafil, thanks. Was looking at Ceebis brand, I suppose it's similar to Cipla? I'll try and compare its potency to the brand stuff.

[NeuroNootropic]

I'm in the same situation except my libido has been dead for more than 4 years now. I try to not let it bother me, but it's something that I just can't seem to forget about. A healthy libido is important for a normal life. Without a libido many people don't see the point of relationships.

 

In my experience, dopaminergics don't increase libido, but rather enhance it. There's a big difference in that if you already have a normal libido then dopaminergics are very likely to heighten it, but if your libido is nonexistent then dopaminergics are unlikely to do much. I think libido, particularly sexual desire (lust), comes from a social connection. If you can't socialize or form friendships then that's probably the reason why you don't have a libido. All the substances I've taken which have increased my libido have also increased my desire to socialize.

 

Some of these substances were Rhodiola, Wellbutrin, Maca, and Moclobemide. Modafinil also seems to help. I've tried both Selegiline and Rasagiline, Methlyphenidate and Vyvanse, but none of these increased my libido nor my desire to socialize. In fact, Selegiline seems to reduce the positive effects I get from the substances that do help.

 

This is just my experience though. I suffer from severe anhedonia and chronic fatigue which is a factor in my response to these substances.

[VerdeGo]

I find the same is true for me. The more a substance disinhibits me and makes me more sociable, the more I see an increase in my libido. In the far past, it was GHB. Now it's theanine, Tazo Chamomile Calm tea, and the adaptogen cordyceps, though cordyceps produces a milder, longer-lasting effect. 

 

If you have low testosterone levels, I don't see how taurine could hurt. A 180% increase of testosterone in animal studies and no side effects in human trials sounds promising. Plus it seems to be a life extender and is widely consumed, so if testosterone is the issue, I'd start there. 

[Baten]

Libido is still low I think it's getting better. Just have a long road ahead, time and patience will help.

 

PDE5 inhibitors do too, lol. Pretty weird at that, Cialis isn't supposed to induce lust, but I am one hundred percent sure it does just that when I am under its effect.

 

Taurine, I'm not sure to be honest. My problems shouldn't be testosterone-related. And reading this iherb review puts me off a little.

 

The phosphatidyl serine before bed time seems to have a subtle but noticeably effect. Also taking some Huperzine I had lying around. Acetylcholine supps seem good for me. I was considering buying some CDP choline too, but remember I didn't react well to it in the past: bouts of depression etc.

[Plasticperson]

Prescript assist.. It's The best probiotic that has humic and fulvic acids. Humic and fulvic modulate the opioid system and facilitate the transfer of minerals into and out of the cell.. Believe me it'll bring meaning wood back better than anything.

[Baten]

Prescript assist.. It's The best probiotic that has humic and fulvic acids. Humic and fulvic modulate the opioid system and facilitate the transfer of minerals into and out of the cell.. Believe me it'll bring meaning wood back better than anything.

 

Mm, I'll give it a try. Thank you.

[platypus]

5mg of tadalafil is a smallish dose, you might want to take that sublingually or carefully experiment with using grapefruit juice to inhibit CYP3A4 which is responsible for metabolizing tadalafil. Using a larger dose of generic tadalafil might be the preferred option though..

[Baten]

5mg of tadalafil is a smallish dose, you might want to take that sublingually or carefully experiment with using grapefruit juice to inhibit CYP3A4 which is responsible for metabolizing tadalafil. Using a larger dose of generic tadalafil might be the preferred option though..

 

Hey, I'm taking the 5mg sublingually, thanks. Grapefruit isn't a bad idea but for now I don't really need to up the potency. I have Indian generic ones on order which I'll be trying out soon, once they arrive. Hope they are as potent as the real thing.

[Area-1255]

 

5mg of tadalafil is a smallish dose, you might want to take that sublingually or carefully experiment with using grapefruit juice to inhibit CYP3A4 which is responsible for metabolizing tadalafil. Using a larger dose of generic tadalafil might be the preferred option though..

 

Hey, I'm taking the 5mg sublingually, thanks. Grapefruit isn't a bad idea but for now I don't really need to up the potency. I have Indian generic ones on order which I'll be trying out soon, once they arrive. Hope they are as potent as the real thing.

 

Have you tried  PT-141?

Edited by Area-1255, 01 May 2015 - 08:29 PM.

[Junk Master]

I'd run a little Epistane to knock down your estrogen levels and then a little DAA.  After that, I agree with Area-1255, I'd shoot a little PT-141 in very small doses at first, then adjust up.

 

Beyond that, we'd have to get into HRT.

[Baten]

I'd run a little Epistane to knock down your estrogen levels and then a little DAA.  After that, I agree with Area-1255, I'd shoot a little PT-141 in very small doses at first, then adjust up.

 

Beyond that, we'd have to get into HRT.

 

I ordered some DIM to knock down estrogen a notch and/or boost testosterone, but my hormone levels should actually be fine. Still, having high T levels might be what I want?

 

PT-141 sounds amazing, almost too good to be true. I'll definitely try it some time, although shooting up sounds a little scary.

[Junk Master]

It's an insulin needle, so nothing like I.M. steroids.  No pain.  However, there is an undeniable psychological barrier.

[Baten]

Libido is still low I think it's getting better. Just have a long road ahead, time and patience will help.

 

[...]

 

Things are getting worse again, sigh. Libido is sometimes 100% dead upon waking up, having a hard time to then get out of that state of mind...

 

Cabergoline arrived last week, official Pfizer Dostinex. Dosed half a tablet of 0.5 mg, so 0.25mg both Monday and Thursday. As a dopamine receptor agonist, people reported that they "could thing of nothing but sex", well hell it didn't do a thing for me. First time I dosed I felt a little "weird", but I didn't notice anything at all for the remainder of the week. Gonna have to try 2x 0.5mg next. Could try taking some daily but that's probably too much ...

 

Also got some Cordyceps which are supposedly good for 100 and more things, well no real results on the libido spectrum either. Too bad.

 

Finally, my indian Tadalafil and Selgin arrived. Gonna give those a try some time... but I'm really starting to lose hope here :(

[platypus]

Does porn still work? If yes you could always masturbate a couple of times a day but never until orgasm. One would think that at some point you'd be tempted by your girlfriend...

[Baten]

Does porn still work? If yes you could always masturbate a couple of times a day but never until orgasm. One would think that at some point you'd be tempted by your girlfriend...

 

I actually tried this before, as far as I know it works counterproductively, similarly to edging: stimulation but without the climax is supposedly even worse.

 

About dopamine, cabergoline+selegiline is insane. Took 2x 5mg of Selgin some hours ago, with cabergoline still being active. I'm feeling seriously better than ever. I'm not sure how long-lasting this is, but the combination is super synergistic. Also proves that the bulk of my problems is dopamine-related, at least that's what I believe now.

Edited by Baten, 06 May 2015 - 12:25 PM.

[Guardian4981]

You may want to try 5-MTHF, it surprisingly helped my libido after trying a lot of other things you mentioned.

[Baten]

You may want to try 5-MTHF, it surprisingly helped my libido after trying a lot of other things you mentioned.

 

I'll try it out, thanks!

[Area-1255]

 

Does porn still work? If yes you could always masturbate a couple of times a day but never until orgasm. One would think that at some point you'd be tempted by your girlfriend...

 

I actually tried this before, as far as I know it works counterproductively, similarly to edging: stimulation but without the climax is supposedly even worse.

 

About dopamine, cabergoline+selegiline is insane. Took 2x 5mg of Selgin some hours ago, with cabergoline still being active. I'm feeling seriously better than ever. I'm not sure how long-lasting this is, but the combination is super synergistic. Also proves that the bulk of my problems is dopamine-related, at least that's what I believe now.

 

Told ya that combination would be boss.  

[platypus]

 

Does porn still work? If yes you could always masturbate a couple of times a day but never until orgasm. One would think that at some point you'd be tempted by your girlfriend...

 

I actually tried this before, as far as I know it works counterproductively, similarly to edging: stimulation but without the climax is supposedly even worse.

 

Well, masturbation is natural and healthy, unless one goes to extremes. Didn't you say your problems started when you stopped watching porn? I hope you did not start to feel that there's something "wrong" with masturbation ...

[Plasticperson]

ill send you a prescript assist sample if you want free of charge

[NeuroNootropic]

You may want to try 5-MTHF, it surprisingly helped my libido after trying a lot of other things you mentioned.

 

Can you elaborate on that? In what ways has it helped your libido?

 

Did you get a blood test to see if you have a MTHFR mutation?

[Guardian4981]

 

You may want to try 5-MTHF, it surprisingly helped my libido after trying a lot of other things you mentioned.

 

Can you elaborate on that? In what ways has it helped your libido?

 

Did you get a blood test to see if you have a MTHFR mutation?

 

 

 

I have not gotten the test, I would like to get the 23 and me test soon.

 

I would say it has helped my libido in two ways.  First is seems to help overall circulation, my units feels more full and sensitive.  2nd I feel more relaxed overall which helps me feel more apt to want some action.

[Baten]

Currently experimenting with the following:

 

-At the beginning of the week: 1x 0.25mg Cabergoline, next day 2x 5mg selegiline in the afternoon + full tablet of Ceebis tadalafil in the evening.

After that no more caber/selegiline, the body seems to do its own thing from there. Taking extra cialis as needed.

Very effective regimen so far, hoping for long-lasting results.

 

-In the weekends I take a shake of Maca+Cocoa+Yohimbine, also taking lysine+taurine+theanine tablet of each to take off the edge,

as well as using my remaining tongkat ali plus some DIM that I bought. Also using some leftover Horny Goat Weed with bioperine.

Not sure about all these so far, but I hope it augments my testosterone/hormone balance. Yohimbine is really stimulating though.

 

-Also started a detox stack with Glutathione, Vitamin C, Spirulina, kidney tonic formula and drinking lots of tea. Also taking zinc picolinate.

Taking these with lunch, just trying to rejuvenate my body. I'm thinking it can only help. Who knows.

 

-Then there's my other stack which I take with dinner. High dose of Pycnogenol, Bromelain, Quali-C, L-Arginine, Green Tea capcules and Cordyceps.

This stack greatly increases erection strength, but doesn't seem to do much for my libido. I'm okay with increased erection strength too, though.

 

-Finally, using up my Phosphatidyl serine capsules, lots of them before sleep with a tablet of 6% mucuna pruriens. Reduces cortisol and makes me sleep well.

Also ordered Citrulline + Arginine powder to drink before bedtime, which I'll take with Prescript Assist and/or some other humic-fulvic formula, for (hopefully) better morning wood.

Edited by Baten, 09 May 2015 - 08:40 AM.

[Baten]

Also considering trying Rhodiola since its effect seems comparable to Selegiline, but this thread kinda scares me off. Isolated rare cases, or...?

Also the description of what happened sounds frighteningly a lot like my initial situation, except that I can't pinpoint the cause.

Edited by Baten, 09 May 2015 - 04:41 PM.

[fntms]

Careful with the phosphatidyl serine, it can make you bleed (one of the rare supplements that did make me bleed). Don't take 'lots' ... Green tea extract also thins the blood.