33 replies to this topic

[Diego55]

I wonder, if there is anyone who has tried vortioxetine mostly as monotherapy for any kind of anxiety issues (especially for social phobia ) for some period of time with any success ?

I have been suffering from crippling social anxiety disorder, depression and other (mostly) anxiety related issues for many years. I have tried over 40+ meds (including Nardil) without any success so far.. I wonder if Brintellix could help me to reduce from these problems ? Thanks.

[OneScrewLoose]

Sorry for the late response. Yes, it's quite possible, at least with social anxiety. It's a near full agonist at 5-HT1a (vortioxetine, not vilazodone), which releases oxytocin. It won't fix everything, but it might give you the foundation you've been looking for, something to build upon.

[YoungSchizo]

Well, a little update again.

 

These past 2 weeks I bumped up Latuda to 111mg and kept Mirtazapine on 15mg. My cognitive function still was really fucked up and together mixed with positive symptoms, I still haven't been able to figure out why my cognition have had plummeted so hard. Maybe because I dropped the high dosage of Mirtazapine after so many years, maybe because of the (strong) interaction with Latuda, I have no clear idea. Anyway, I have no side-effects anymore from Latuda which is also a bit weird but may also be because of the (strong) interaction with Mirtazapine, but again, I have no clear idea.

 

Since my mood stabilized on Latuda, (it kinda is a antidepressant on it's own) I decided to drop Mirtazapine altogether this past weekend. Maybe a bit too early to judge but I'm two days in and I notice more clarity in my chaotic mental state I've been in this past 3-4 weeks so I hope this isn't coincidence and will improve more over the coming few days. I'll update again on this case, but one thing is for sure, Latuda and high dosages of Mirtazapine, great(!) though, unfortunately it also ignites fire I'm unable to have control over, damn!  

 

Well, whatever is going to happen, with Mirtazapine out of my life I've got myself a ticket to get me some new chemical meat; Vortioxetine.  

[YoungSchizo]

My last update regarding Latuda and Mirtazapine. It's been well over 9 days since stopping Mirtazapine, it turned out to be a good choice since they have a strong interaction.

 

My mood is stable but I'm slowly getting a bit down though, anxiety rises also a bit, these symptoms may partially be due to lack of sleep I have since I stopped Mirtazapine.

 

Here and there I'm reading about Vortioxetine that it may not be a good drug after all like all type antidepressant that affect Serotonine and thereforet one should not expect more than the effects of older type antidepressant already on the market. Since Vortioxetine is a new molecular entity I'd expected more enthusiasm, can someone maybe chime in about what makes Vortioxetine a good/different antidepressant/antianxiety drug? (If my drug dealers accept my request I will be taking Vortio somewhere next week.)