• Log in with Facebook Log in with Twitter Log In with Google      Sign In    
  • Create Account
  LongeCity
              Advocacy & Research for Unlimited Lifespans

Photo
- - - - -

Old rat brains rejuvenated and new neurons grown by asthma drug

montelukast

  • Please log in to reply
3 replies to this topic

#1 MacTum

  • Guest
  • 4 posts
  • 2
  • Location:Sydney
  • NO

Posted 24 October 2015 - 11:50 AM


 

It’s as good as new. An asthma drug has rejuvenated rat brains, making old rats perform as well as young rats in tests of memory and cognition. The drug also encouraged the birth of new brain cells.

As we get older, most of us will experience some kind of brain degeneration. Typically, we lose the ability to make new neurons. Another problem is chronic, low-grade inflammation in the brain, which is implicated in many age-related brain disorders.

 

 

A drug called montelukast (Singulair), regularly prescribed for asthma and allergic rhinitis, blocks these receptors, so Aigner and his colleagues tried it on young and old rats. The team used oral doses equivalent to those taken by people with asthma.

 

https://www.newscien...-GLOBAL-twitter

 

Sounds interesting for older people...


Edited by MacTum, 24 October 2015 - 11:50 AM.

  • Informative x 5
  • like x 1

#2 resveratrol_guy

  • Guest
  • 1,315 posts
  • 290

Posted 25 October 2015 - 05:20 AM

Impressive! The effect might be enhanced by rofecoxib. Rarely, the drug may have caused a nonspecific cognitive disorder. All in all, side effect profile seems relatively tame for a pharmaceutical, considering how many asthmatics are likely taking this.



sponsored ad

  • Advert
Click HERE to rent this advertising spot for BRAIN HEALTH to support LongeCity (this will replace the google ad above).

#3 di36

  • Guest
  • 67 posts
  • 13
  • Location:EU

Posted 25 October 2015 - 10:23 AM

that is a very usual drug for people with asthma



sponsored ad

  • Advert
Click HERE to rent this advertising spot for BRAIN HEALTH to support LongeCity (this will replace the google ad above).

#4 LongLife

  • Guest
  • 145 posts
  • 19
  • Location:Peru

Posted 02 January 2016 - 11:54 PM

Impressive! The effect might be enhanced by rofecoxib. Rarely, the drug may have caused a nonspecific cognitive disorder. All in all, side effect profile seems relatively tame for a pharmaceutical, considering how many asthmatics are likely taking this.

ROFECOXIB (Vioxx by manufacturer Merck) was voluntarily taken off the market in 2004 due to heart conditions developing in users.

 

SEE: http://www.fda.gov/D...s/ucm106290.htm







Also tagged with one or more of these keywords: montelukast

2 user(s) are reading this topic

0 members, 2 guests, 0 anonymous users