5 replies to this topic

[lemon_]

Hi,

 

- Fasting inhibits mTOR. 

- If you search for mTOR inhibitors you will find loads, but most of them will inhibit the mTOR in the liver,kidney,etc,etc. We need it in the brain. 

 

Here is a photo of the synapse look with MDMA (long term)

 

 

(Left) Excess synapses in the brain of a child with autism (Right) Properly pruned synapses of a developmentally typical child.

 

 

Children with autism have overactive mTOR, which prevents autophagy from ‘cleaning house’ and getting rid of the damaged synapses.

[YOLF]

Hmmm... maybe it's time for me to do a few days of water only fasting. That stuff's good for all sorts of stuff, not just drug tolerances, but also hormesis and rejuvenation.

[toto75015]

I've tried a ten days water fast 2 years ago.

 

I've never experienced such a peace of mind since my childhood.

 

Unfortunately the feelings stays only a few days after the end of the fast, and a week or two after I was back to my old self (slight depression, social anxiety, disthymia...).

 

Nevertheless, I will definitely try it again, and probably fast regularly once or two per year for 10 to 20 days, as a reset of my body and mind.

 

The most difficult parts of fasting to my experience are:

 

- to start (you'll always find multiple reasons to delay a fast)

- the first few days (after day 2 you'll lose the hunger feelings, and the psychological hunger is totally gone after day 4)

 

You should check Valter Longo researches on fast and cancer, it's really interesting.

[BobbyDick]

 

 

Ketogenic diet inhibits mTOR signaling in hippocampus and liver of normal rats.

http://onlinelibrary...11.02981.x/full

 

Fasting is in the some way high-fat, low-carb diet.

[meatsauce]

I wonder if all this neurogenesis nootropics like dihexia and nsi-189 is actuality moving some users closer to autism. After a while of taking nsi-189 I would feel awkward in some social setting and feel way too much in my head. I am normally very good in social interactions.

[sativa]

To restore/reset drug tolerances, Iboga/memantine/lobelia are effective.