i'm not going to draw any lines in the sand by overextending myself to say, 'you are surely high choline and norepinephrine' or 'high choline equates with sluggish cognitive tempo' or anything to that effect. ginkgo would work better if you had ADHD. maybe it will still work on you? sometimes it's best not to 'pigeonhole' individuals with this or that disease or neurotransmitter deficiency, because low and high levels of a neurotransmitter can cause striking similar side effects, because a neurotransmitter may be elevated in one region while simultaneously being lowered in another, because neurotransmitters interact in curious ways which science has yet to unravel, and because non-invasive measurements of serum levels can hardly be used to predict brain levels
as for the resources you requested:
Symptoms of High Acetylcholine. ←take this one with a grain of salt tho
Acetylcholine in Anxiety States (1952).
New biochemical changes found in children with ADHD (2011).
overthinking, or rumination, generally points to anxiety. hard to tell.. can also be OCD + psychotic disorder, and ADHD is like a mini-schizophrenia disorder? generally these people have co-morbid depression and anxiety, but a small fraction may be unafflicted 'pure' OCD + ADHD groups. not clear how dopamine, norepinephrine, serotonin and acetylcholine co-operate here.. and the 5-HT2c receptor throws a wrench in the mix, as usual
o-cha is legit. i would check out zencha.net, specifically products from Yame. they are all first flush, except the sencha moe which is half first & half second. first flush has higher theanine, more fishy/umami taste. also, you should be able to steep those 30minutes without anxiety-issues. personally i steep mine in a rather radical way, pulverized with a mortar and pestle and brewed like matcha but stirred constantly, at 100 C, with lemon, brown sugar and royal jelly
I absolutely agree with you it's best not to pigeonhole people. Also, as you remarked, maybe gingko will benefit me. It's really hard to say without first giving it a go. I recall I did take ginkgo many years ago, but it was a different brand and I don't recall ever noticing any striking effect one way or another. As to the rest of what you wrote in that paragraph, amen to that.
FWIW, I'm currently completing a bachelor degree in nursing. I'm in my early 40'ies, so attending university is kind of tough, especially in that very demanding field. I was recently told by one of my nursing supervisor that I'd have been a better MD than a nurse. The reason why she said that, is because I know more about human physiology and neurophysiology than is required by my course of studies. So these things are really my forte. Less so when it comes to true nursing stuff - I guess It's more of a female vs male thing. The #1 thing my fellow students have been telling me is that I think too much. There are both up and downsides to this.
Thanks for the Zencha.net link, as I about to place a tea order with O-cha, but instead I'll give Zencha a go. I recall reading that Zencha is also one of the top Japanese tea vendor. However, I'd forgotten about it. Over at O-cha, I usually order Chiran sencha (first-flush). Actually most of O-cha's teas are first flush. What I wanted to say is that I've indeed noticed that I do not have anxiety issues when I brew first-flush sencha for ~10 minutes. However, two weeks ago, I ordered O-cha's daily sencha (second flush), used same amount of I usually do (1 tsp), same temp (75 C), but after days of doing that, I ended up feeling both anxious and quite depressed. I'm going back to first-flush.
So tea is a cholinergic ? I've never looked into this topic.
So you basically end up eating your sencha. The ascorbic acid I know increases the bioavavailability of green tea polyphenols. Any specific reason for the brown sugar and royal jelly ? Also, what brand of royal jelly have you been using ? It looks like it's something I could benefit from as you suggested above. Again, thanks for taking the time to respond - it's kind of you.
Wrt to the first of the three URL you linked me to, I do have many of the listed symptoms of high Ach. However, I do not seem to run into problems when having eggs or other high choline sources. I actually had three eggs today and feel quite good, but what I mean by this is I felt quite good before I had said eggs and saw no change whatsoever thereafter. However, as is indicated in the link you sent, Ach can be higher for other reasons than merely dietary choline intake.
Don't hesitate if you have any questions.
Come to think of it, I did try gotu Kola a number of years ago - it felt the way you described. But from what I can remember I benefit more from lion's mane than gotu kola as far as calm clear energy goes.
FWIW, the only medicinal mushroom I cannot tolerate (at least when taken alone) is red reishi. I find it too sedating and it causes brain fog. This might have to do with it's effect on the histamine H3 receptor IIRC.
I was once diagnosed with OCPD and it makes sense because nurses are known to have OCPD traits. Even out of the nursing context, I'd certainly agree I do at least have traits of OCPD. However, when it comes to the diagnostic of personality disorders, this whole subject is somewhat of a mess, as is the whole field of mental health. What I mean by this is on a given day, depending on the circumstances in one's life, one might be diagnosed with NPD, while at a different time, it might be OCPD. Clearly, I'm preaching to the choir here, as I'm convinced you've long been aware of the flaws inherent to the field of mental health, which btw is an area I really enjoy. I've really enjoyed training in the psych ward. I can better deal with the type of stresses in the psych ward than those in general medicine, but I digress.
Edited by chipdouglas, 10 January 2017 - 11:17 PM.