Hmm, interesting note here, btw - I just realized that maybe Kappa-antagonism can help with an aspect of schizotypy which is a bit unexpected...
If you have hard to treat positive symptoms - voices telling you that you suck, et c, then, perhaps... Kappa antagonism can change them - or at least the way you respond to the hallucinations, and then in turn their nature.
In places like Africa and India, where family-structure, society and beliefs, differ from the West, many schizo's actually report a DIFFERENT quality to their delusions: they are actually more benign.
Some of the angst and pain and depression that comes from schizo, is apparently cultural... Christianity really did a number on our civilization.
In Africa at least, there is a faith in spirits, natural and familial, which then extends to the schizos: they believe the voices are their deceased loved ones, trying to help them in their life - telling them jokes and giving advice in tricky situations.
Now, I probably shouldn't be saying this, because, HELL, it probably won't work, but maaaaybe, maaybe... Kappa-antagonism will change the way you respond to the voices? (if you have them) - living with Schizo wouldn't be half as hard if the voices were actually COOL for once, instead of being DICKS, like they are here in the West.
There might be something to it though - if you feel no punishment, then how can you fear the voices? How can they hurt you? The answer is, perhaps, in no fucking way whatsoever.