2 replies to this topic

[vader]

Very surprised with the effects of thiamine HCL on verbal fluency, energy levels and overall cognition. Dosed 2 - 4mg every 4 to 6 hours (to saturate the pathways, more can only be absorbed through passive diffusion, so unless extremely deficient then throwing on 100mg+ is pointless).

 

It could be caused by my chronic alcoholism, but overall it's GOAT! Magnesium, cinnamon and full RDA multi stacks well.

 

No wonder my alcohol intake and coffee drinking depleted me out of thiamine.

 

Discuss.

[Michael Rian]

The Thiamine I take daily comes in 100mg tablets, this was the lowest dose I could find other than getting it in a Complex.

 

There are multiple studies on Pubmed of using High Dose Thiamine, 600mg - 1500mg, for things like chronic fatigue, MS, Alzheimers, PD, and a few other conditions. It is a very fascinating Vitamin for sure. I will try and find some of the studies.

 

I have never heard of the super low dose you have been using, but still very interesting, Glad you have found something that helps!!

[Michael Rian]

Long-Term Treatment with High-Dose Thiamine in Parkinson Disease: An Open-Label Pilot Study. - PubMed - NCBI

 

Evidence for a central cholinergic effect of high-dose thiamine. - PubMed - NCBI

 

Case Report: High-dose thiamine improves the symptoms of fibromyalgia

 

Pharmacokinetics of high-dose oral thiamine hydrochloride in healthy subjects

 

High-dose thiamine improves fatigue after stroke: a report of three cases. - PubMed - NCBI

 

High-dose thiamine improves the symptoms of Friedreich's ataxia. - PubMed - NCBI

 

High-dose thiamine therapy counters dyslipidemia and advanced glycation of plasma protein in streptozotocin-induced diabetic rats. - PubMed - NCBI

 

Preliminary findings of high-dose thiamine in dementia of Alzheimer's type. - PubMed - NCBI

 

 

Thiamine and Fatigue in Inflammatory Bowel Diseases:

An Open-label Pilot Study

http://online.lieber...9/acm.2011.0840