Hi gcurrie,
Firstly, many thanks for your input. I've read a few of your posts on other threads recently and I like your common-sense approach to assessing the qualities of various noot's.
I have not noticed any negative *or* positive effects from > 100 mcg of Huperzine per day. As a result, I consider it a waste to take more.
I take it that you DO perceive positive effects from 100mcg then?
Pyritinol does appear to me to have a wider optimum dose range, so it might be worth adjusting it as needed.
Do you think there's any problem with bouncing around with pyritinol dosage on a day-to-day basis? I'm toying with the idea of not taking it every day at all, but 400mg-1200mg some days of the week, as I feel the need.
Vinpocetine is a staple for me, and I take 40-60 mg daily. Vincamine I have tried, and it feels mostly like more vinpocetine. I can *feel* it more, but that's not necessarily a good thing to me. I see no compelling reason to do both on a regular basis. YMMV.
Reading through all the anecdotes/info I could find on this forum and others, vinpocetine does seem to work better for most. But I found a few exceptions. LifeMirage, for instance, has said that he personally gets more from vincamine and that it has certain effects beyond vinpocetine. I intend to experiment and hopefully find what works for me. What kind of combined doses of vinpocetine and vincamine did you try before deciding to bypass the vincamine? Did you ever try the vinca by itself?
I have not heard that vinpocetine/vincamine (as selective cerebral vasodilators) increase cerebral hemorrhage risk. Pyritinol doesn't have the same level of vasodilation as v/v. Picamilon is much more of a vasodilator, for example.
There was a discussion about vasodilators (though mainly about gingko) here:
http://www.imminst.o..... clots&st=140As with most things it seems to come down to not overdoing it one way or the other. I think I'll avoid adding ginkgo to this stack though. I believe Pyritinol significantly increases CBF which mightn't be quite the same thing as the arterial dilation effects of vasodilators. Nevertheless, as all three are having effects on cerebral blood circulation I'm interested in people's opinions of the maximum safe dosage combination. Obviously I want to avoid even the slightest increase to the risk of cerebral hemorrhage.
I would recommend that you add piracetam. I think the net effect might be more substantial. Just because you don't notice local effects doesn't mean that you won't find yourself spinning fantastic logical webs and thought connections and wondering "Where did THAT come from?"
It concerned me that some people have reported sleepiness or lack-of-focus when taking racetams. As I want to target mental energy/focus/stamina, I certainly don't want to complicate my stack with something counterproductive to those aims. Especially as I spent the first half of this year getting on top of a hypothyroid condition (Hashimoto's thyroiditis). Creative thinking is actually my strong suit, and while I'd love to improve it still further, memory, processing speed, etc. remain my priorities. I notice on the thread about which racetams are the best that you've posted a comment that the "spaced out" effect has mainly been reported by people trying aniracetam. Do you think it's less of a concern with piracetam? This might be the key issue for me in determining whether to add it to the stack.