537 replies to this topic

[nickdino]

Is tamari healthier than soysauce? What about the whole estrogen story of soybeans and tamari?

[tintinet]

I'm not too concerned:

http://www.pcrm.org/...-the-expert-soy

Edited by tintinet, 23 February 2017 - 11:37 AM.

[Cube]

A synthetic form of sulforaphane

http://www.evaluateg...Story&id=534658

[Snejks]

which you recommend very good brand quality, high concentration, price for sulforaphane? How much dosage per day?

[Iporuru]

A nice write-up of the health benefits of broccoli sprouts and sulforaphane: https://selfhacked.c...s-sulforaphane/

[scooterboy]

I am going to start making Broccoli Sprout smoothies from Rhonda Patrick's video but what she don't tell you is how often should you drink them in a week . Every day , every other day , three days a week .  Anyone no ?

[Nate-2004]

She eats/drinks them every day except on weekends when she's not at home. It's in that interview video.

 

I finally got all the sprouting supplies and got my first sprouts going, just had some today. 3rd day is supposedly highest in sulforaphane outside of seeds. I poured a cup of 69 degree celsius water on it, blended it for a sec, then let it sit till the temp dropped to about 53, then drank it like a shot. I'd be interested to see how it tastes in one of the variations on her smoothie that I make.

Edited by Nate-2004, 27 February 2017 - 10:57 PM.

[mmortal03]

The only problem with Nrf2 induction is the inhibition of Melanogenesis, so probably you are at risk of acelerating gray hair

Well, there are also concerns that it might promote atherosclerosis. From the paper linked to below:

Altogether, it seems clear that Nrf2 expression can promote atherosclerosis via systemic and/or vascular local effects that can vary depending on the type of diet administered, despite its anti-oxidant actions.

http://www.futuremed...0.2217/clp.12.5

[mmortal03]

http://www.sciencedi...308814613019419

Rather ominous for mustard seed, ISTM.

 

How much erucic acid might be in a 1/4 teaspoon of common varieties of mustard powder, or if you ground your own from the seeds? The abstract says that "a careful selection of mustard cultivars could lower the nutritional intake of erucic acid."

[DareDevil]

A synthetic form of sulforaphane

http://www.evaluateg...Story&id=534658

Hi Cube,

 

This Irish product isn't yet on the market, however it is said to contain a dosage of 43mg/capsule of sulforaphane. While some say it is very low, maybe it depends on the bioavailability of various forms of sulforaphane?

 

For example this French one, declared by another Longecity member to have 70% bioavailability, is dosed at only 10mg/capsule. They say to not exceed 30mg to 60mg/day:

 

http://www.prostapha...rostaphane.html

 

I would like to better understand what target dosage might be useful. I plan to buy a pack of 90 capsules and test Prostaphane at various doses.

 

Cheers,

 

DareDevil

Edited by DareDevil, 01 March 2017 - 06:38 AM.

[Harkijn]

Well, there are also concerns that it might promote atherosclerosis. From the paper linked to below:

Altogether, it seems clear that Nrf2 expression can promote atherosclerosis via systemic and/or vascular local effects that can vary depending on the type of diet administered, despite its anti-oxidant actions.

http://www.futuremed...0.2217/clp.12.5

 

This is no small matter. I think that those who consider supplementing or eating large amounts of broccoli sprouts on a permanent basis should think again.

 

I wonder if Dr. Patrick knows about this study...

[Cube]

https://www.google.c...Z6obVF9uNe9L7gA

This study was comparing broccomax with fresh broccoli sprouts. Broccomax came out no good even though they claim to have myrosinase

Edited by Cube, 01 March 2017 - 07:30 AM.

[Andey]

https://www.google.c...Z6obVF9uNe9L7gA

This study was comparing broccomax with fresh broccoli sprouts. Broccomax came out no good even though they claim to have myrosinase

 

  That was the old formulation of Broccomax - without myrosinase.

[Nate-2004]

Well, there are also concerns that it might promote atherosclerosis. From the paper linked to below:

Altogether, it seems clear that Nrf2 expression can promote atherosclerosis via systemic and/or vascular local effects that can vary depending on the type of diet administered, despite its anti-oxidant actions.

http://www.futuremed...0.2217/clp.12.5

 

This is no small matter. I think that those who consider supplementing or eating large amounts of broccoli sprouts on a permanent basis should think again.

 

I wonder if Dr. Patrick knows about this study...

 

This is a single negative study in the face of numerous positive studies, I would hold off on any panic till it can be reproduced at *least* once. That, or an association made in humans.

[Nate-2004]

 

https://www.google.c...Z6obVF9uNe9L7gA

This study was comparing broccomax with fresh broccoli sprouts. Broccomax came out no good even though they claim to have myrosinase

 

  That was the old formulation of Broccomax - without myrosinase.

 

 

Right, this study is from 2011 and BroccoMax did not start adding myrosinase till last year.

[mmortal03]

 

Would rinsing the final sprouts in a weak solution of bleach kill any harmful bacteria without effecting the sprout quality, taste, or nutritional content?

Yikes bleach!

 

There is precedence for using bleach, if done properly, as per one of the Fahey papers, in how they made their Broccoli seed powder: https://www.ncbi.nlm...les/PMC4629881/
 

Broccoli seed powder (BSdP) was made by surface disinfesting seeds of broccoli (Brassica oleracea var. italica) with 25% Clorox bleach, followed by extensive rinsing with distilled water and drying.

[Harkijn]

 

Well, there are also concerns that it might promote atherosclerosis. From the paper linked to below:

Altogether, it seems clear that Nrf2 expression can promote atherosclerosis via systemic and/or vascular local effects that can vary depending on the type of diet administered, despite its anti-oxidant actions.

http://www.futuremed...0.2217/clp.12.5

 

This is no small matter. I think that those who consider supplementing or eating large amounts of broccoli sprouts on a permanent basis should think again.

 

I wonder if Dr. Patrick knows about this study...

 

This is a single negative study in the face of numerous positive studies, I would hold off on any panic till it can be reproduced at *least* once. That, or an association made in humans.

 

You are right Nate. I put it too alarmist. We'll see.

[Nate-2004]

 

You are right Nate. I put it too alarmist. We'll see.

 

 

Having read the study just now it seems his main concern is a problem of inflammation. The mice used also lack LDL from what I understood. And also, he poses the possibility of this being completely dependant on diet. An anti-inflammatory diet may resolve this problem. I take curcumin, krill oil/fish oil, ginger and other anti-inflammatory cocktails not to mention near infrared light therapy. I doubt this is a problem for most of us.

[Harkijn]

https://www.google.c...Z6obVF9uNe9L7gA

This study was comparing broccomax with fresh broccoli sprouts. Broccomax came out no good even though they claim to have myrosinase

It was already pointed out that Broccomax has taken the criticism to heart.

Still I appreciate Cube's posting this link, because I had not heard about the 'interconversion' of glucophoranin and glucoerucin. Per the authors this is a good thing.

I knew erucin only as a 'bad guy', but apparently isothyanates achieve more if working together. I would appreciate very much if someone could point to studies that elucidate this cooperation.

[Cube]

Thanks for the heads up andey and nate! I should have looked for the date they changed broccomax. I was hoping Jarrow was honest as i have used some of their products. So there is still hope in supplementing sprout powder!. Although I'll try mason jar method Seeds here are near $20 for 100g quarantine won't let any in from overseas. think I'll try growing broccoli and cultivating seeds looks like you average 5000 per plant.

[Nate-2004]

I discovered that it's really upsetting to the stomach if I eat too many broccoli sprouts. I have been warming them up to 69°C with water and blending them. I'm not sure exactly how much I should be eating her day but a little over a cup of this will really upset my stomach.

[j87]

According to Rhonda's video,
1 gram of fresh broccoli sprouts = 2.4 umol sulforaphane (0.425 mg)

According to Super Sprouts
1TBSP broccoli sprout powder (5 grams) = 125 grams fresh broccoli sprouts
http://usa.superspro...coli-equals.jpg

60mg sulforaphane = 140g fresh sprouts

5.64 grams powder = 60mg sulforaphane  

Although Super Sprouts wouldn't reply to my emails asking how much glucoraphanin is contained in a serving, and they don't show the research paper conducted on their powder (they only talk about it).

Nutricargo broccoli sprout powder at $44/kilo is much cheaper than Super Sprouts. Assuming the calculations above are correct, Nutricargo might give 177 servings of 60mg sulforaphane (not the concentrated extract, just the normal broccoli sprout powder). I'm not sure if the myrosinase is at risk of degrading in the powder, if so it might be required to eat daikon or mustard seed powder with it. Currently this seems like the easiest/cheapest way to get sulforaphane. Thoughts?

Edited by j87, 06 March 2017 - 03:20 AM.

[nickdino]

I discovered that it's really upsetting to the stomach if I eat too many broccoli sprouts. I have been warming them up to 69°C with water and blending them. I'm not sure exactly how much I should be eating her day but a little over a cup of this will really upset my stomach.

I had an issue after eating brocolli sprouts too, i got sick shortly after. I put them in 60 degrees for 10 minutes, froze them and blended them into a smoothie.

[Cube]

j87

I think tablespoon would be closer to 14g
Teaspoon should be about 5g

[Nate-2004]

I e-mailed Jarrow to find out the following:

 

Your BroccoMax product now contains the enzyme myrosinase which is required to convert the glucoraphanin to sulforaphane. Shouldn't it be refrigerated? Have there been any tests on how long the enzyme survives as far as shelf-life is concerned? How are you adding myrosinase? What is the extraction process and from what?

 

Their response:

 

Hi Nathan,

Thank you for your e-mail query to Jarrow Formulas. Based on the stability tests we have conducted, it is not necessary to keep BroccoMax in refrigeration. Additionally, we have conducted stability tests that demonstrate the myrosinase is stable for the shelf life of the product (two years).

BroccoMax is extracted via a Co2 extraction method. The origin of the myrosinase is also broccoli.

If you would like to learn more about the manufacturing of the raw material, please see the following link for the patent:

http://www.google.co...tents/US9017666


Jarrow Formulas,Inc.

info@jarrow.com 

[j87]

j87

I think tablespoon would be closer to 14g
Teaspoon should be about 5g

 

According the the Super Sprouts label 5g is 1tbsp https://images-na.ss...51VZID9ijBL.jpg

 

I forgot something though, according to this faq, glucoraphanin + myrosinase (as in not the stabilized sulforaphane, or fresh sprouts blended) has a bio-availability of 35% http://chemoprotecti...sked-questions/

 

Assuming the sprout powder is the same as glucoraphanin + myrosinase (if you add mustard/daikon), then it would only give you maybe 21mg sulforaphane per 5g (not sure). Although Super Sprouts claim their powder has a higher bioavailability  the same as fresh sprouts (but wont post the actual study or answer questions, so I'm not sure I believe them).

[Cube]

Cheers j78
Broccomax should yield after conversion 8mg sulforaphane per capsule so I'm guessing 3 per day for 70kg/150lb body wieght might be a good place to start.
I'm living in a very hot humid climate so my sprouts are a bit iffy atm but will take them in combination when the situation suits. Also taking niacel and quercetin hopefully a nice combo. Will lets you guys know if i notice anything significant.

[Castiel]

Cheers j78
Broccomax should yield after conversion 8mg sulforaphane per capsule so I'm guessing 3 per day for 70kg/150lb body wieght might be a good place to start.
I'm living in a very hot humid climate so my sprouts are a bit iffy atm but will take them in combination when the situation suits. Also taking niacel and quercetin hopefully a nice combo. Will lets you guys know if i notice anything significant.

It would be good to know the quantity of myrosinase in broccomax and test how much it can convert. As it is a catalyst it should be able to convert some quantity of any additional precursor from cooked broccoli or other sources that were consumed along with it.

[Castiel]

Will add, dont know if it was posted, but there was recent research showing sulforaphane aids in fat browning.

https://www.scienced...70307100402.htm

Browned fat, white turned beige burns calories all its own. So in addition to inhibiting myostatin potentially increasing muscle it also seems to help reduce fat by browning, both mechanisms helping to get cut.

[Andey]

Will add, dont know if it was posted, but there was recent research showing sulforaphane aids in fat browning.

https://www.scienced...70307100402.htm

Browned fat, white turned beige burns calories all its own. So in addition to inhibiting myostatin potentially increasing muscle it also seems to help reduce fat by browning, both mechanisms helping to get cut.

 

  Interesting, thanks. Hopefully it also have some synergy with Wim Hof method or general cold exposure that also should increase brown fat.

Edited by Andey, 08 March 2017 - 04:28 PM.