31 replies to this topic

[Florian E.]

It would definitely be nice to have some human senescent cell accumulation statistics by age...

 

In the meanwhile i will continue to avoid senescent cells as much as possible with trying to keep proper GSH/CAT/SOD metabolism, NAD+ and autophagy.

http://www.reactome....#/R-HSA-2262752

 

mTOR inhibitors (that inhibit both mTORC1 & mTORC2) help to push cells towards autophagy instead of senescence. (https://www.ncbi.nlm...les/PMC4789579/)

And afaik, in the ongoing search for better rapalogs, rapamycin is still the best (available) option to achieve that.

[Florian E.]

deleted

Edited by Florian E., 11 April 2017 - 12:14 AM.