2291 replies to this topic

[zorba990]

You need at least 100-120 mg PQQ. Turnbuckle said that PQQ was the crucial supplement that made it all work. High dose required.

Do we have a reliable brand for PQQ?

[Blueflash]

Do we have a reliable brand for PQQ?

[Blueflash]

Im using a brand called BestVite. I chose it because it doesn’t have too many fillers. I can feel more focused, better memory and enhanced gym performance with it.

[Advocatus Diaboli]

Bestvite seems to be an efficient operation. They do the manufacturing and distributing of more than 200 products (look above the "7-Keto" bottle on this page). Not too shabby for a company of 7 to maybe 15 employees. Their manufacturing facilities must be pretty impressive. Also, they have earned a reputation of being "The most trusted name in vitamins"--USPTO says so.  

Edited by Advocatus Diaboli, 18 November 2024 - 03:24 PM.

[PAMPAGUY]

https://cdn.consumerlab.com

 

 

HSN and Doublewood were cheapest per 20mg and passed test

[stephen_b]

I took 2g AAKG and 100 mg PQQ in the morning. At 6 PM that day I did a shorter 3.5 mile run which was better than average.

 

The following morning though I set a recent PR for push-ups at 60. Recently I had not been able to do more than a mid-40's count of push-ups. I wonder if the maximization of the benefits take more than 1 day.

 

I think I'm going to avoid taking the regular fission supplements (N+R 1 g, AAKG 1 g, PQQ 20 mg). The 2g AAKG and 100 mg PQQ feels much more restorative.

[kurt9]

This new protocol is cheaper and certainly much easier than the regular one.

[Repack Racing]

This protocol has had ZERO effect on anything related to athletics for me.

[stephen_b]

I was unaware of sulforaphane being a big fusion promoter.

 

Sulforaphane is a Nrf2-independent inhibitor of mitochondrial fission. 

 

We demonstrate here that the mitochondria of cultured, human retinal pigment epithelial (RPE-1) cells treated with SFN undergo hyperfusion that is independent of both Nrf2 and its cytoplasmic inhibitor KEAP1.

 

 

[stephen_b]

In Turnbuckle's earlier post on restoring mitochondrial function (link), the protocol is:

 

Fission: 500mg niacinamide, 1g AAKG, and 20mg PQQ

Fusion: 300mg DHM, 1g AAKG, and 20mg PQQ

 

I have not felt much benefit from the DHM. I'd like to propose 1g Meriva curcumin in its place, with or without Broccomax sulphurophane.

 

 

Mitochondrial Physiology and Vegetal Molecules

 

 

Curcumin has been reported to enhance the fusion activity, reduce fission machinery, and increase biogenesis and synaptic proteins. Elevation in mitochondrial function and cell viability has been shown with curcumin treatment. Curcumin might improve mitochondrial potential and ATP and restore mitochondrial fusion, probably by upregulating PGC-1α protein expression.

 

Edited by stephen_b, 10 February 2025 - 05:50 PM.

[kurt9]

Would the single dose of 100-120 mg of PQQ along with the AAGK be considered the replacement for the above/

[stephen_b]

Would the single dose of 100-120 mg of PQQ along with the AAGK be considered the replacement for the above/

 

I was under the impression that the PQQ/AAKG was for mitochondrial methylation issues he spoke of in the reversing MS article as opposed to normal mitochondrial errors.