164 replies to this topic

[GABAergic]

they couldnt tell me, i asked. i assume its there then. but it will probably so small, comparison to canola oil, its nothing. but thanks to you mentioning this toxin, i did research on it, and it probably explains the heart problems associated with food using canola oil, especially fried stuff

 

for the person who asked for references, i just read about it on wiki; https://en.wikipedia...iki/Erucic_acid

Edited by GABAergic, 20 June 2019 - 01:24 AM.

[ChristineH]

they couldnt tell me, i asked. i assume its there then. but it will probably so small, comparison to canola oil, its nothing. but thanks to you mentioning this toxin, i did research on it, and it probably explains the heart problems associated with food using canola oil, especially fried stuff

 

I guess we'd have to assume it is below the FDA limit.

[Castiel]

BTW, I did look at all the supplements you listed, but didn't find anything practial. Frankly, the dosages of the active ingredients are either so low, and/or the cost of each is so high, that none of these look like sensible options for obtaining sulforaphane. So I'm sticking with eating broccoli florets in combination with white radish as frequently as I can bear. People prefer magic bullets, of course. So do I, actually. But in this case, I don't think they exist.

 

 

You don't want to go too high either.   It is said 4 cups of broccoli sprouts in some cases might already reach upper limits wherein it starts being detrimental rather than beneficial and starts causing dna damage.  Depending on preparation even 1 cup of sprouts might reach the limit.

 

6 cups of the old broccomax formulation had only a small fraction of the sulforaphane in sprouts.   But I heard they have a new formulation that is significantly more effective.  Also don't know about avmacol formulation, but it should probably be better than the older broccomax formula.

ref-

https://www.longecit...-18#entry852820

 

 Here it seems 40micromole of sulforaphane has some degree of effectiveness.  6mg is 32micromole, if I'm not mistaken, so not that far off what shows benefits in at least some things.

 https://www.ncbi.nlm...les/PMC6804255/

Edited by Castiel, 19 September 2020 - 02:55 AM.

[parsons]

Any experiences or opinions regarding https://www.amazon.c...s/dp/B07QW9VLSZ  (the company is now just referred to as SMNutrition)?  It's pretty cheap compared to some of the others and does have myrosinase and glucoraphanin

Edited by parsons, 25 October 2020 - 12:39 PM.

[ChristineH]

Hello Parsons,

 

The label claims are inconsistent and partly meaningless.  The broccoli seed extract BroccoRaphanin claims to provide 7.5 mg glucoraphanin. If there were no losses in production (unlikely), the maximum sulforaphane per capsule would be 3 mg.  The Broccophane claiming 0.4% is meaningless as sulforaphane is unstable.

 

You would not know if the mustard has active myrosinase. Bioperine is not known to enhance sulforaphane absorption; it is used for polyphenols like curcumin.

 

Whomever formulated this product has very poor knowledge of sulforaphane chemistry.

 

You say the product is cheap – it would need to be.  I work on a daily dose of 20 mg sulforaphane for a therapeutic effect.  That would mean 7 of these capsules.  You only get what you pay for!

 

[parsons]

Hello Parsons,

 

The label claims are inconsistent and partly meaningless.  The broccoli seed extract BroccoRaphanin claims to provide 7.5 mg glucoraphanin. If there were no losses in production (unlikely), the maximum sulforaphane per capsule would be 3 mg.  The Broccophane claiming 0.4% is meaningless as sulforaphane is unstable.

 

You would not know if the mustard has active myrosinase. Bioperine is not known to enhance sulforaphane absorption; it is used for polyphenols like curcumin.

 

Whomever formulated this product has very poor knowledge of sulforaphane chemistry.

 

You say the product is cheap – it would need to be.  I work on a daily dose of 20 mg sulforaphane for a therapeutic effect.  That would mean 7 of these capsules.  You only get what you pay for!

Thanks for this.  what brand(s) do you recommend?  I was now thinking about going with Avmacol now.  

[Gal220]

Recommendation thread HERE

[ChristineH]

Thanks for this.  what brand(s) do you recommend?  I was now thinking about going with Avmacol now.  

Avmacol claim their product yields 4 mg per capsule.  (Potential conflict of interest by me).  My company, Cell-Logic produces Enduracell Plus which yields 14-15 mg per capsule.  This is availabel through Cell-Logic Australia or Cell-Logic-USA.

[onz]

Sulforaphane expert Dr. Jed Fahey's interview with Dr. Rhonda Patrick:

 

 

 

• 00:00:00 - Intro discussion of Dr. Fahey and his work.

• 00:04:36 - Beginning of Q&A Session

• 00:04:36 - QUESTION: What is the minimum daily dose of sulforaphane that has been shown to provide health benefits? How much sulforaphane does a 200-gram serving of broccoli or broccoli sprouts contain?

• 00:09:21 - The difficulty with estimating how much sulforaphane is in a given weight of sprouts.

• 00:12:38 - QUESTION: Where does Jed Fahey get his broccoli seeds from?

• 00:14:54 - QUESTION: Does adding ground mustard seed to a cooked cruciferous vegetable increase the amount of sulforaphane in it? Referenced study

• 00:20:55 - QUESTION: If one can’t consume broccoli sprouts every day, how beneficial is it to consume them only after exposure to heavy air pollutants? As a firefighter I am exposed to a lot of carcinogens during a fire and am wondering if it’s beneficial to only take them post fire calls and for how many days. Referenced studies: 1, 2

• 00:28:24 - QUESTION: How long do the health benefits of broccoli sprouts last? Would consuming them every day be better than consuming every other day or once a week.

• 00:31:36 - QUESTION: Does sulforaphane increase detoxification of heavy metals and pesticides?

• 00:36:45 - QUESTION: On the Kevin Rose podcast Rhonda mentioned that broccoli sprouts increase the production of glutathione in the brain. So I was wondering what your thoughts are on continuous supplementation. If taken long-term would the brain stop producing it naturally? Referenced study

• 00:40:29 - QUESTION: Are there any studies that you know of that would suggest broccoli sprouts would be beneficial for a person who has already been diagnosed with cancer? If so, which cancers? Referenced study

• 00:47:53 - QUESTION: What are the potential benefits of sulforaphane for Alzheimer’s disease? Editor's note: There is an on-going clinical trial.

• 00:54:18 - QUESTION: Is it necessary to sprout broccoli seeds or can you get sulforaphane by just blending and eating the seeds?

• 00:57:27 - QUESTION: Are there negative health effects from consuming erucic acid?

• 01:00:25 - QUESTION: Are broccoli sprouts still the best way to get Sulforaphane? How to maximize production in the sprouts? Freeze them, steep them, both? Let them sit after blending to allow the myrosinase to react with the glucoraphanin?

• 01:04:28 - How to make broccoli sprouts more palatable without compromising the health benefits.

• 01:08:18 - QUESTION: What are your thoughts on the recent study: Microwave cooking increases sulforaphane level in broccoli.

• 01:12:21 - QUESTION: What is the best way to store broccoli sprouts once grown in a big batch?

• 01:14:43 - Alternatives to broccoli sprouting.

• 01:14:43 - QUESTION: Is there any research to indicate the most bioavailable way to consume moringa?

• 01:22:45 - QUESTION: What brands of sulforaphane supplements do you consider reliable?

• 01:30:25 - Safety concerns of sulforaphane.

• 01:30:33 - QUESTION: What are your thoughts on Dr. Paul Saladino's comments on the JRE podcast? Does swimming in cold water have the same effect as eating sulforaphane?

• 01:36:45 - QUESTION: Does sulforaphane have a goitrogenic effect? Is there concern over thyroid health? Referenced studies: 1, 2, 3

• 01:48:25 - QUESTION: What is the upper limit of safety for consuming broccoli sprouts and eruric acid?

[onz]

They've started selling Broccoli sprouts in Japanese super markets!!!

 

It looks to be claiming 214mg of sulforaphane per 50g packet - but this seems super high from what I've been reading about sprouts, any thoughts?

 

Either way I'm happy I don't have to pay for expensive supps anymore or mess around with the chore of sprouting them all the time haha

 

 131596496_241349397388459_6892150549049182330_n.jpg   147.73KB   3 downloads

[aribadabar]

They've started selling Broccoli sprouts in Japanese super markets!!!

 

It looks to be claiming 214mg of sulforaphane per 50g packet - but this seems super high from what I've been reading about sprouts, any thoughts?

 

Either way I'm happy I don't have to pay for expensive supps anymore or mess around with the chore of sprouting them all the time haha

 

131596496_241349397388459_6892150549049182330_n.jpg

 

You have 214mg of of Sulforaphane Glucosinolate (SGS), not sulforaphane - which requires the enzyme myrosinase be converted to sulforaphane. In real-life conversion/metabolism, that yields about 1/3-1/5 the amount in sulphoraphane depending on gut flora and myrosinase availability.

Edited by aribadabar, 15 December 2020 - 10:05 PM.

[ChristineH]

They've started selling Broccoli sprouts in Japanese super markets!!!

 

It looks to be claiming 214mg of sulforaphane per 50g packet - but this seems super high from what I've been reading about sprouts, any thoughts?

 

Either way I'm happy I don't have to pay for expensive supps anymore or mess around with the chore of sprouting them all the time haha

 

131596496_241349397388459_6892150549049182330_n.jpg

 

The SGS appearing amidst the Japanese text is a marketing term - sulforaphane glucosinolate is really glucoraphanin (GRN), the precursor.  The packet therefore contains only 214 mg GRN for the entire packet which is about 4 mg per gram of sprouts.  If the enzyme is intact, as it should be in fresh sprouts, eating the whole packet might yield about 86 mg sulforaphane.  That might seem impressive but fresh sprouts also contain an enzyme inhibitor (epithiospecifier protein) which can inhibt 75 - 90% of the myrosinase enzyme.  Therefore, it is more likely that the fresh sprouts would yield between 9 - 20 mg sulforaphane for the entire 50 gram packet.

The SGS appearing amidst the Japanese text is a marketing term - sulforaphane glucosinolate is really glucoraphanin (GRN), the precursor.  The packet therefore contains only 214 mg GRN for the entire packet which is about 4 mg per gram of sprouts.  If the enzyme is intact, as it should be in fresh sprouts, eating the whole packet might yield about 86 mg sulforaphane.  That might seem impressive but fresh sprouts also contain an enzyme inhibitor (epithiospecifier protein) which can inhibt 75 - 90% of the myrosinase enzyme.  Therefore, it is more likely that the fresh sprouts would yield between 9 - 20 mg sulforaphane for the entire 50 gram packet.

The SGS appearing amidst the Japanese text is a marketing term - sulforaphane glucosinolate is really glucoraphanin (GRN), the precursor.  The packet therefore contains only 214 mg GRN for the entire packet which is about 4 mg per gram of sprouts.  If the enzyme is intact, as it should be in fresh sprouts, eating the whole packet might yield about 86 mg sulforaphane.  That might seem impressive but fresh sprouts also contain an enzyme inhibitor (epithiospecifier protein) which can inhibt 75 - 90% of the myrosinase enzyme.  Therefore, it is more likely that the fresh sprouts would yield between 9 - 20 mg sulforaphane for the entire 50 gram packet.

[onz]

Just a heads up, our next guest on the Longecity podcast is Christine Houghton, she completed her PhD on sulforaphane so now's the time to ask any questions you may have!

 

Post your questions in the comments on the podcast thread, the interview will take place on 8th July. Sulforaphane expert - Dr. C...

Edited by onz, 28 June 2021 - 05:29 AM.

[APBT]

If this is true and accurate, there isn't much bioavailable sulforaphane in most products:  https://www.broq.life/compare

 

[stockcarman]

I eat a teaspoon of B seeds and a teaspoon of mustard seeds every day . No problem here .