Pretty small study group but a strong result. The popular science article stated they received both curry and curcumin powder. The study PDF only mentions Curcumin capsules, 6x250mg
CONCLUSIONS A 9-month curcumin intervention in a prediabetic population significantly lowered the number of prediabetic individuals who eventually developed T2DM. In addition, the curcumin treatment appeared to improve overall function of β-cells, with very minor adverse effects. Therefore, this study demonstrated that the curcumin intervention in a prediabetic population may be beneficial.
The impacts of type 2 diabetes mellitus (T2DM) on global health care and economy are enormous (1). According to the World Health Organization, there are ∼311 million people worldwide who live with T2DM. This number continues to rise, especially in the newly developing and poorer countries in Asia and elsewhere. Because T2DM is currently incurable, a common treatment approach is to try to control the disease with lifelong use of antidiabetes drugs. Limiting the number of newly developed T2DM cases should be one of the better key strategies to restrict the global impacts of T2DM (2). In order to limit the number of new T2DM cases, the lifestyle of the prediabetic population has to be changed. However, this has been shown to be challenging (3). One of the alternative approaches to prevent development of T2DM is to intervene with the prediabetic population before disease progresses into fully developed T2DM (3). The intervention approach is appealing. It relies on timely identification of prediabetic individuals and provision of preventive treatment before the disease fully progresses. The intervention represents a chance for the diabetes-prone population to halt the disease progression and maintain a normal and healthy life. In recent years, several effective T2DM intervention regimens have been developed, with encouraging results (3–5). However, these regimens are not usually economically accessible, and they are not well-tolerated because of treatment-related toxicities (4,5). The focus now is to identify new effective therapeutic agents, with relatively low cost and low toxicity, that can be used regularly to control a progression of T2DM in the prediabetic population.
Curcumin is the principal curcuminoid found in turmeric (Curcuma longa Linn.), a popular spice in Asian cuisine. It is widely consumed and generally believed to be beneficial for human health (6). Curcumin extract from rhizomes of turmeric has been shown to contain anti-inflammation and antidiabetic properties (7–13). In addition, it could delay development of T2DM, improve β-cell functions, prevent β-cell death, and reduce insulin resistance in animals (8–16). This study aimed to determine the effectiveness of curcumin extract as an intervention agent to prevent T2DM development. We assessed T2DM progression and several indicative T2DM parameters in a large randomized, double-blinded, and placebo-controlled cohort. We found that curcumin extract effectively reduced the number of prediabetic individuals who progressed toward T2DM as well as improved functions of β-cells.
The interventionAll participants were instructed to takethree capsules with blinded labels ofeither curcumin or placebo twice a day(total of six capsules per day) for 9months continuously. Each curcumincapsule has curcuminoid content of 250mg. Curcumin and identical placebo cap-sules were manufactured by the Govern-ment Pharmaceutical Organization ofThailand. Patients were asked to bringall capsules back at the follow-up visit at3, 6, and 9 months for assessing theircompliance. Numbers of capsules takenby the subjects were recorded (Supple-mentary Table 3
http://care.diabetes...1.full-text.pdf
