Allergies do serve a purpose, and could be a marker of our susceptibility to different spectrums of aging disease as I see it. I'm considering getting a customized total allergy vaccine which would eliminate my allergies by introducing the allergens to my blood stream or deeper tissues. Though as I've given it some thought, I've gotten my allergens into open, bleeding wounds, and gotten local and diffuse allergic reactions such as rash and itching, so the idea of a direct injection, whether into blood or subcutaneously is a little scary. Perhaps it will work for some allergens, but where it doesn't, might it lead to anaphylaxis?
And if it works as it's supposed to, will it affect my lifespan? Allergies lead to the immune system removing cells earlier in their lifecycle, so wouldn't that slow aging to some extent? If allergy genetics are part of my healthy aging where they do not lead to serious pathology, then some moderate allergies would be good to have depending on how and at what time they affect the cell lifecycle and could be leveraged as senolytic pathway by instead managing my lifestyle better.
What are your thoughts? Does anyone have information on precisely how these work, especially as it relates to aging pathologies?